Found 30 Enz. Inhib. hit(s) with Target = 'Urease' and Ligand = 'BDBM50229993' TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataKi: 1.96E+4nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+4nM IC50: 2.10E+4nMAssay Description:Reaction mixture consisting of 25 µL of Jack bean (Canavalia ensiformis) urease (1 unit/well), 55 µL of 100 mM urea dissolved in phosphate buffer (4 ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+4nM IC50: 2.10E+4nMpH: 6.8Assay Description:Reaction mixtures consisting of 25 μL (1 unit/well) of Jack bean (Canavalia ensiformis) urease, 55 μL of buffer at pH 6.8, 100 mM of urea, ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Competitive inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Lineweaver-Burk/Dixon plot analysi...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition of Canavalia ensiformis (jack bean) urease assessed as release of ammonia after 30 min by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 1.95E+4nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by Weatherburn assayMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMpH: 6.8 T: 2°CAssay Description:Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean urease by phenol red methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffers containing 100 mM urea were incubated with 5 ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Canavalia ensiformis (jack bean) urease using urea as substrate after 15 min by indophenol-based spectrophotometric analysisMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Canavalia ensiformis (jack bean) urease assessed as inhibition of ammonia production after 15 min by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition assay using urease from jack bean.More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:The synthesized compounds (4a-e, 5a-e) were tested for their in vitro urease inhibition activities at 0.2 mM concentration against jack bean urease. ...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMpH: 6.8 T: 2°CAssay Description:Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffer containing 100 mM urea were incubated with 5 &...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.11E+4nMAssay Description:In vitro inhibition assay using jack bean urease.More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of jack beans urease assessed as hydrolysis of urea into ammonia preincubated for 10 mins followed by urea addition measured after 10 mins...More data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production incubated at 30 degC for 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as reduction in ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 6.83E+5nMAssay Description:Inhibition of Jack bean urease using urea as substrate assessed as production of ammonia after 15 minsMore data for this Ligand-Target Pair
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Comsats Institute Of Information Technology
Curated by ChEMBL
Comsats Institute Of Information Technology
Curated by ChEMBL
Affinity DataIC50: 6.83E+5nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 minsMore data for this Ligand-Target Pair
