Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'VHL complex' and Ligand = 'BDBM454884'
TargetVHL complex(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454884(US10730870, Example 47 | US11512083, Example 47)
Affinity DataIC50:  178nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetVHL complex(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454884(US10730870, Example 47 | US11512083, Example 47)
Affinity DataIC50:  339nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent