Report error Found 192 with Last Name = 'he' and Initial = 'zx'
Affinity DataKi: 8.30nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity to DCN1 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 810nMAssay Description:Binding affinity to DCN4 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.14E+3nMAssay Description:Binding affinity to DCN5 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.88E+4nMAssay Description:Binding affinity to DCN2 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.24E+4nMAssay Description:Binding affinity to DCN4 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.89E+4nMAssay Description:Binding affinity to DCN5 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 6.62E+4nMAssay Description:Binding affinity to DCN2 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.85E+5nMAssay Description:Binding affinity to DCN3 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.92E+5nMAssay Description:Binding affinity to DCN3 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 0.0190nMAssay Description:Inhibition of human recombinant c-MET in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 0.0230nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of human recombinant c-MET in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of c-MET (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human full length PARP1 expressed in Escherichia coli rosetta (DE3) incubated for 20 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human full length PARP1 expressed in Escherichia coli rosetta (DE3) incubated for 20 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of PARP1 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of N-terminal His-tagged p300 HAT (unknown origin) (1287 to 1666 residues) expressed in Escherichia coli using biotinylated H3(1-21) pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
