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Found 4355 with Last Name = 'taylor' and Initial = 'am'
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataKi:  1.20E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataKi:  2.50E+3nMAssay Description:Mixed inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataKi:  2.50E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataKi:  6.30E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304354(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)
Affinity DataKi:  3.00E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304354(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)
Affinity DataKi:  3.90E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataKi:  4.20E+4nMAssay Description:Mixed inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataKi:  4.30E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345367(1-cyclobutyl-4-(1-tetralin-6-ylsulfonyl-4,5-dihydr...)
Affinity DataIC50:  0.0160nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345352(4-[4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroi...)
Affinity DataIC50:  0.0210nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345355(1-cyclobutyl-4-[1-[4-(3-thienyl)phenyl]sulfonyl-4,...)
Affinity DataIC50:  0.0210nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345354(1-cyclobutyl-4-[1-[4-(2-thienyl)phenyl]sulfonyl-4,...)
Affinity DataIC50:  0.0270nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345410(1-cyclobutyl-4-(1-indan-5-ylsulfonyl-4,5-dihydroim...)
Affinity DataIC50:  0.0310nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345351(3-[4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroi...)
Affinity DataIC50:  0.0340nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345393(1-cyclobutyl-4-[1-[4-(1,1-dimethylpropyl)phenyl]su...)
Affinity DataIC50:  0.0350nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345350(2-[4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroi...)
Affinity DataIC50:  0.0370nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345376(US10202354, Example 41)
Affinity DataIC50:  0.0390nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345408(1-cyclobutyl-4-[1-[(6-methoxy-2-naphthyl)sulfonyl]...)
Affinity DataIC50:  0.0410nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345409(1-[1-[(6-chloro-2-naphthyl)sulfonyl]-4,5-dihydroim...)
Affinity DataIC50:  0.0410nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345366(1-cyclobutyl-4-(1-((4-isopropylphenyl)sulfonyl)-4,...)
Affinity DataIC50:  0.0430nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345360(1-cyclobutyl-4-[1-[4-(2-fluorophenyl)phe-nyl]sulfo...)
Affinity DataIC50:  0.0460nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345377(US10202354, Example 42)
Affinity DataIC50:  0.0470nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345349(1-cyclobutyl-4-[1-(4-phenylphenyl)sulfonyl-4,5-dih...)
Affinity DataIC50:  0.0480nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345389(1-cyclobutyl-4-[1-(3-phenylphenyl)sulfonyl-4,5-dih...)
Affinity DataIC50:  0.0490nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345380(2-(4-cyclobutylpiperazin-1-yl)-3-(4-isopropylpheny...)
Affinity DataIC50:  0.0490nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345364(1-cyclobutyl-4-[1-[4-(2-methylpyrazol-3-yl)phenyl]...)
Affinity DataIC50:  0.0490nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345363(1-cyclobutyl-4-[1-[4-(1-methylpyrazol-3-yl)phenyl]...)
Affinity DataIC50:  0.0490nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345400(1-cyclobutyl-4-[1-(4-phenoxyphenyl)sulfonyl-4,5-di...)
Affinity DataIC50:  0.0500nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345359(1-cyclobutyl-4-[1-[4- | US10202354, Example 24)
Affinity DataIC50:  0.0500nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345336(2-[4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroi...)
Affinity DataIC50:  0.0530nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345381((R)-1-cyclobutyl-4-[1-(4-isopropylphenyl)sulfonyl-...)
Affinity DataIC50:  0.0540nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345369(1-cyclobutyl-4-[1-(4-cyclopropylphenyl)sulfonyl-4,...)
Affinity DataIC50:  0.0580nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345365(5-[4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroi...)
Affinity DataIC50:  0.0600nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345396(1-cyclobutyl-4-[1-(2-naphthylsulfonyl)-4,5-dihydro...)
Affinity DataIC50:  0.0620nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345414(5-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroimid...)
Affinity DataIC50:  0.0620nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345362(1-cyclobutyl-4-[1-[4-(4-fluorophenyl)phe-nyl]sulfo...)
Affinity DataIC50:  0.0710nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345344(1-cyclobutyl-4-[1-[4-(m-tolyl)phenyl]sulfonyl-4,5-...)
Affinity DataIC50:  0.0740nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345413(1-cyclobutyl-4-[1-[(6-methyl-2-naphthyl)sulfonyl]-...)
Affinity DataIC50:  0.0770nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345343(1-cyclobutyl-4-[1-[4-(o-tolyl)phenyl]sulfonyl-4,5-...)
Affinity DataIC50:  0.0770nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345338(1-cyclobutyl-4-[1-[4-(4-methoxyphenyl)phe-nyl]sulf...)
Affinity DataIC50:  0.0800nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345388(1-[4-tert-butylphenyl)sulfonyl-4,5-dihydroimidazol...)
Affinity DataIC50:  0.0810nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345356(1-[1-[4-(2-chlorophenyl)phe-nyl]sulfonyl-4,5-dihyd...)
Affinity DataIC50:  0.0840nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345370(1-cyclobutyl-4-[1-(3-cyclopropylphenyl)sulfonyl-4,...)
Affinity DataIC50:  0.0870nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345391(1-cyclobutyl-4-[1-(3,5-dimethylphenyl)sulfonyl-4,5...)
Affinity DataIC50:  0.0880nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345405(N-[4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroi...)
Affinity DataIC50:  0.0940nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345353(1-cyclobutyl-4-[1-[4-(4-pyridyl)phenyl]sulfonyl-4,...)
Affinity DataIC50:  0.0950nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345340(4-[4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroi...)
Affinity DataIC50:  0.0970nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345337(1-cyclobutyl-4-[1-[4-(3-methoxyphenyl)phe-nyl]sulf...)
Affinity DataIC50:  0.0980nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345339(1-cyclobutyl-4-[1-[4-[2-(trifluoromethyl)phe-nyl]p...)
Affinity DataIC50:  0.102nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345341(1-cyclobutyl-4-[1-[4-(2-pyridyl)phenyl]sulfonyl-4,...)
Affinity DataIC50:  0.102nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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