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Found 855 of ic50 for UniProtKB: Q86WV6
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604466(CHEMBL5201766)
Affinity DataIC50:  0.0623nMAssay Description:Binding affinity to recombinant human His-tagged STING by measuring fluorescent signals in the presence of d2 labelled STING wild type ligand by HTRF...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604556(CHEMBL5175703)
Affinity DataIC50:  0.200nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509399(CHEMBL4468010)
Affinity DataIC50:  0.300nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509421(CHEMBL4577528)
Affinity DataIC50:  0.700nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50547941(CHEMBL4755632)
Affinity DataIC50: <1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50547938(CHEMBL4787511)
Affinity DataIC50: <1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50547937(CHEMBL4757897)
Affinity DataIC50: <1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50547940(CHEMBL4800391)
Affinity DataIC50: <1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50547942(CHEMBL4764478)
Affinity DataIC50: <1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50547939(CHEMBL4755510)
Affinity DataIC50: <1nMAssay Description:Competitive binding affinity to human recombinant C-terminal Avi-tag STING using Alexa 488 probe incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM573971(US11453697, Example 247)
Affinity DataIC50:  1.10nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509408(CHEMBL4459563)
Affinity DataIC50:  1.30nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509422(CHEMBL4476079)
Affinity DataIC50:  1.40nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM573856(US11453697, Example 20)
Affinity DataIC50:  1.40nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509431(CHEMBL4589856)
Affinity DataIC50:  1.5nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604561(CHEMBL5197904)
Affinity DataIC50:  1.70nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataIC50:  1.80nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604563(CHEMBL5201164)
Affinity DataIC50:  1.90nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604560(CHEMBL5180005)
Affinity DataIC50:  2nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50511088(CHEMBL4457089)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type STING (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604555(CHEMBL5181746)
Affinity DataIC50:  2.90nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604562(CHEMBL5185127)
Affinity DataIC50:  3.10nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509412(CHEMBL4474321 | US11453697, Example 1)
Affinity DataIC50:  3.5nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604559(CHEMBL5174023)
Affinity DataIC50:  3.70nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataIC50:  3.90nMAssay Description:Displacement of fluorescein-labelled probe from human cytoplasmic domain of STING G230A/R293Q double mutant (155 to 341 residues) by time-resolved FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50604557(CHEMBL5191008)
Affinity DataIC50:  4.20nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50587689(CHEMBL5197229)
Affinity DataIC50:  4.60nMAssay Description:Agonist activity at human STING incubated for 3 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of anti 6His antibody-labeled terbium cryptate binding to human wild-type full-length 6His-tagged d2-labeled STING measured after 4 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataIC50:  6.20nMAssay Description:Binding affinity to recombinant human His-tagged STING by measuring fluorescent signals in the presence of d2 labelled STING wild type ligand by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataIC50:  7.10nMAssay Description:Displacement of fluorescein-labelled probe from wild type human His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50558665(CHEMBL4776666)
Affinity DataIC50:  7.20nMAssay Description:Displacement of fluorescein-labelled probe from human cytoplasmic domain of STING G230A/R293Q double mutant (155 to 341 residues) by time-resolved FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509430(CHEMBL4570468)
Affinity DataIC50:  8.30nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634270(US20230357253, Compound 168)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634127(US20230357253, Compound 6)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634276(US20230357253, Compound 174)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634279(US20230357253, Compound 177)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634284(US20230357253, Compound 182)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634292(US20230357253, Compound 191)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634294(US20230357253, Compound 194)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634295(US20230357253, Compound 195)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634299(US20230357253, Compound 199)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634304(US20230357253, Compound 204)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634305(US20230357253, Compound 205)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509425(CHEMBL4566174 | US11453697, Example 27)
Affinity DataIC50:  10nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634129(US20230357253, Compound 8)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634131(US20230357253, Compound 10)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634139(US20230357253, Compound 19)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634168(US20230357253, Compound 56)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634171(US20230357253, Compound 59)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM634177(US20230357253, Compound 66)
Affinity DataIC50: <10nMAssay Description:An assay format was optimized to demonstrate binding of recombinant 6×His-tagged human STING protein labeled with Terbium Cryptate by the natural lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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