TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0780nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.200nM EC50: 5.80nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at human GHSR1a receptor assessed as intracellular Ca2+ concentration by aequorin luminescent assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration of the compound (biotinylated probe) is evaluated for [35S]- MK-0677 bindingMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inverse agonist activity at rat ghrelin receptor expressed in HEK293 cells by NFAT-RE-luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1aMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nM EC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nM EC50: 3nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Binding affinity towards cloned human Growth hormone secretagogue receptor type I in LLC PK-1 cells using [125I][His9]-ghrelin as radioligandMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of the compound against human growth hormone secretagogue (GHS) receptorMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.420nMAssay Description:Binding affinity to cloned human growth hormone secretagogue receptor type 1 in a competitive binding assay with [35S]-MK-0677 as a radiolabeled liga...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.420nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.5nM EC50: 0.600nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Ability to displace [125I]ghrelin from cloned human Growth hormone secretagogue receptor type I (GSH1a) receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.530nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.600nM EC50: 1.60nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Competitive binding assay using ghrelin receptor.More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.620nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.630nMAssay Description:Binding affinity towards human Growth hormone secretagogue receptor type 1 using competitive binding assay with radiolabeled [35S]-MK-0677 expressed ...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.670nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Displacement of 125I-[His9]-ghrelin from human GHSR1a expressed in LLC-PK1 cells by competitive binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals
Curated by ChEMBL
Sumitomo Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair