Affinity DataKd: 490nMAssay Description:To determine the dissociation rate of the inhibitor, 1 µM HDAC8 and 20 µM inhibitor (syringe I) were mixed with 100 µM c-SAHA (syringe...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Binding affinity to HDAC8 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 6.80E+3nMAssay Description:To determine the dissociation rate of the inhibitor, 1 µM HDAC8 and 20 µM inhibitor (syringe I) were mixed with 100 µM c-SAHA (syringe...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMpH: 7.5Assay Description:A fixed concentration of 1.5 µM was titrated with an increasing concentration of the respective inhibitor in protein storage buffer containing 5...More data for this Ligand-Target Pair
Affinity DataKd: 580nMAssay Description:Binding affinity to human recombinant HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.40E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.50E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.60E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.50E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.60E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.70E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.70E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.90E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.90E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.30E+3nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.30E+3nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40E+3nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
Affinity DataKd: 75nMAssay Description:Binding affinity to human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 90nMAssay Description:Binding affinity to human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding affinity to human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 38nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 46nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 95nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 95nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.80nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.70nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.5nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.40nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to His-tagged recombinant human HDAC8 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.40nMAssay Description:Binding affinity to HDAC8 (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.60nMAssay Description:Binding affinity to HDAC8 (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.90nMAssay Description:Binding affinity to HDAC8 (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.20nMAssay Description:Binding affinity to HDAC8 (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
Affinity DataKd: 390nMpH: 7.5Assay Description:A fixed concentration of 1.5 µM was titrated with an increasing concentration of the respective inhibitor in protein storage buffer containing 5...More data for this Ligand-Target Pair