Compile Data Set for Download or QSAR
maximum 50k data
Found 391 of ec50 for UniProtKB: Q9Y5N1
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127606(2-(1H-Imidazol-4-yl)-cyclopropylamine | CHEMBL2940...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H3 receptor using [3H]-N-alpha-methyl histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127603(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H3 receptor using [3H]-N-alpha-methyl histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127602(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H3 receptor using [3H]-N-alpha-methyl histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127609(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H3 receptor using [3H]-N-alpha-methyl histamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50150945(CHEBI:81390 | Immepip)
Affinity DataEC50:  0.0398nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50472544(Iodoproxyfan)
Affinity DataEC50:  0.0501nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405121(CHEBI:64151 | CHEMBL1490875)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405121(CHEBI:64151 | CHEMBL1490875)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405122(CHEMBL4159570)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405117(CHEMBL4170869)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405117(CHEMBL4170869)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405122(CHEMBL4159570)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM81542(Beta-Methylhistamine | CAS_565544 | NSC_565544)
Affinity DataEC50:  0.123nMAssay Description:Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50483134(CHEBI:64156 | Imetit)
Affinity DataEC50:  0.126nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50150945(CHEBI:81390 | Immepip)
Affinity DataEC50:  0.126nMAssay Description:Inhibition of cAMP-stimulated beta-galactosidase transcription in SK-N-MC cells expressing human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50150945(CHEBI:81390 | Immepip)
Affinity DataEC50:  0.132nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM22910(4-(1H-imidazol-5-ylmethyl)pyridine | Immethridine)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50212733(CHEMBL425994 | N-(2-((dimethylamino)methyl)-4-(3-(...)
Affinity DataEC50:  0.200nMAssay Description:Inverse agonist activity at human histamine H3 receptor by GTP gammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50321823(4-((1H-Imidazol-4-yl)methyl)-1-(3-(trifluoromethyl...)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405032(CHEMBL4159472)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405116(CHEMBL4177416)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405116(CHEMBL4177416)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50405032(CHEMBL4159472)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human H3R expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50475340(Methimepip)
Affinity DataEC50:  0.316nMAssay Description:Inhibition of cAMP-stimulated beta-galactosidase transcription in SK-N-MC cells expressing human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50215536((R)-Alpha-Methylhistamine | CHEBI:73337 | CHEMBL26...)
Affinity DataEC50:  0.316nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50514105(CHEMBL4441731)
Affinity DataEC50:  0.316nMAssay Description:Agonist activity at human H3R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50475340(Methimepip)
Affinity DataEC50:  0.316nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50474424(CHEMBL153051)
Affinity DataEC50:  0.389nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50483133(Clobenprobit)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM22530(N(alpha)-Methylhistamine | N-alpha-methylhistamine...)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50483132(CHEMBL281576)
Affinity DataEC50:  0.501nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50224191((R)-2-(1-(6-ethoxypyridazin-3-yl)-5-methyl-1H-pyra...)
Affinity DataEC50:  0.590nMAssay Description:Agonist activity at human histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50079575(CHEMBL3417586)
Affinity DataEC50:  0.600nMAssay Description:Inverse agonist activity at human H3R expressed in CHO cells assessed as inhibition of RAMH-induced [35S]GTPgammaS binding relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50514107(CHEMBL4535316)
Affinity DataEC50:  0.631nMAssay Description:Agonist activity at human H3R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50170164(Imbutamine)
Affinity DataEC50:  0.631nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at human histamine H3 receptor expressed in CHO cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50215536((R)-Alpha-Methylhistamine | CHEBI:73337 | CHEMBL26...)
Affinity DataEC50:  0.676nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataEC50:  0.700nMAssay Description:Inhibition of basal activity of human histamine H3 receptor expressed in CHO cells assessed as inhibition of RAHM-induced [35S]GTPgammaS binding afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50079576(CHEMBL3417585)
Affinity DataEC50:  0.700nMAssay Description:Inverse agonist activity at human H3R expressed in CHO cells assessed as inhibition of RAMH-induced [35S]GTPgammaS binding relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50360889(CHEMBL1935100)
Affinity DataEC50:  0.700nMAssay Description:Inverse agonist activity at human histamine H3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50360902(CHEMBL1935114)
Affinity DataEC50:  0.730nMAssay Description:Inverse agonist activity at human histamine H3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50317865(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Affinity DataEC50:  0.75nMAssay Description:Agonist activity at human recombinant histamine H3 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50317865(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Affinity DataEC50:  0.75nMAssay Description:Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50317865(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Affinity DataEC50:  0.75nMAssay Description:Agonist activity at human histamine H3 receptor expressed in CHO cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50224189((R)-2-(4-methyl-2-(pyrrolidin-1-yl)pyrimidin-5-yl)...)
Affinity DataEC50:  0.780nMAssay Description:Agonist activity at human histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50514091(CHEMBL4560428)
Affinity DataEC50:  0.794nMAssay Description:Agonist activity at human H3R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50355121(CHEMBL1835783)
Affinity DataEC50:  0.800nMAssay Description:Inverse agonist activity at human histamine H3 receptor assessed as decrease of basal activity of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50364958(CHEMBL1950743)
Affinity DataEC50:  0.800nMAssay Description:Inverse agonist activity at human histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50355120(CHEMBL1835782)
Affinity DataEC50:  0.800nMAssay Description:Inverse agonist activity at human histamine H3 receptor assessed as decrease of basal activity of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 391 total ) | Next | Last >>
Jump to: