TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Binding affinity to human alpha2beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 34nMAssay Description:Binding affinity to human alpha2beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Binding affinity to human alpha2beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 54nMAssay Description:Binding affinity to human alpha2beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 55nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 67nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 84nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 99nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 101nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 104nMAssay Description:Binding affinity to human alpha2beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 118nMAssay Description:Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 134nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 143nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 154nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 184nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 188nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Activation of human GABAA alpha-2-beta-3-gamma-2L receptor expressed in Xenopus oocytes assessed as modulation of nicotine-induced current by two-ele...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 202nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 238nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 245nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 247nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 256nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 268nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 284nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 327nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 383nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 407nMAssay Description:Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 410nMAssay Description:Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 459nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 650nMAssay Description:Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 661nMAssay Description:Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 737nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 820nMAssay Description:Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 832nMAssay Description:Agonist activity at human GABAAalpha2beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 879nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.08E+3nMAssay Description:Agonist activity at recombinant human GABAA receptor alpha2beta2gamma2L expressed in Xenopus laevis oocytes incubated for 30 secs by electrophysiolog...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 1.16E+3nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Neurogen
Curated by ChEMBL
Neurogen
Curated by ChEMBL
Affinity DataEC50: 1.18E+3nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.63E+3nMAssay Description:Modulation of human GABAA alpha2beta3gamma2 expressed in xenopus oocytes assessed as potentiation of GABA-evoked chloride currentsMore data for this Ligand-Target Pair