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Found 492 of ic50 for UniProtKB: P35355
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472616(CHEMBL65325)
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472618(CHEMBL303092)
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472623(CHEMBL294100)
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472632(CHEMBL65140)
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472624(CHEMBL62439)
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472627(CHEMBL304489)
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289087(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472613(CHEMBL305076)
Affinity DataIC50:  2.10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472612(CHEMBL60496)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472605(CHEMBL64507)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289084(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289082(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289088(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289083(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289081(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472615(CHEMBL64813)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM22970(2-{1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-1H...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472610(CHEMBL60725)
Affinity DataIC50:  9.10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472622(CHEMBL291543)
Affinity DataIC50:  9.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50331888(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:Compound was evaluated in vitro for inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472631(CHEMBL60738)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076661(CHEMBL177727 | N-{1-Ethyl-3-[1-(4-methoxy-phenyl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076666(CHEMBL175153 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50075539(3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,2,4]thia...)
Affinity DataIC50:  11nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472619(CHEMBL62990)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472625(CHEMBL62920)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289090(CHEMBL162776 | {1-[1-(4-Bromo-benzyl)-5-methoxy-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289089(2-[1-(4-Chloro-benzyl)-5-methoxy-2-methyl-1H-indol...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50012860(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289091((S)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-in...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated in vitro for inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472603(CHEMBL65330)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50223539(CHEMBL33957)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076659(CHEMBL435907 | N-{3-[5-(4-Chloro-phenyl)-1-(4-meth...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472609(CHEMBL64585)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076637(CHEMBL369252 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076650(CHEMBL368682 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50:  48nMAssay Description:Binding affinity towards Alpha-1A adrenergic receptor in rat denuded thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260464(CHEMBL4071383)
Affinity DataIC50:  49nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50223541(Clofurac)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076642(2,2,2-Trifluoro-N-hydroxy-N-{3-[1-(4-methoxy-pheny...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50003117(3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-4H-[1,2,4]o...)
Affinity DataIC50:  50nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289087(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated in vitro for inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260465(CHEMBL4101003)
Affinity DataIC50:  53nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472604(CHEBI:35847 | CP-66,248 | Tenidap)
Affinity DataIC50:  53nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50:  56nMAssay Description:Compound was evaluated for its binding affinity against Toxoplasma gondii purine nucleoside phosphorylase of virulent strain RH (value indicates comp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase in rat neutrophilsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076639(CHEMBL367010 | N-{3-[5-(4-Ethyl-phenyl)-1-(4-metho...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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