Compile Data Set for Download or QSAR
maximum 50k data
Found 105 of ic50 for UniProtKB: P14100
LigandPNGBDBM50073692(5-methyl-2-(4-methylpentyl)-(6aR,9aS)-3,4,5,8-tetr...)
Affinity DataIC50:  6nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50:  12nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50:  14nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059032((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...)
Affinity DataIC50:  14nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073695((R)-7-Isopropyl-5-methyl-2-(3-methyl-butyl)-7,8-di...)
Affinity DataIC50:  15nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50:  25nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073700((R)-2-Hexyl-7-isopropyl-5-methyl-7,8-dihydro-3H,5H...)
Affinity DataIC50:  25nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073696(5-methyl-2-pentyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  31nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073702(2-heptyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50:  33nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059062((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...)
Affinity DataIC50:  36nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073697(5-methyl-2-(1-propylbutyl)-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  60nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073704(2-butyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  110nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50289464(3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[c...)
Affinity DataIC50:  110nMAssay Description:Inhibition of bovine aorta phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50073693(2-(1-ethylpropyl)-5-methyl-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50:  150nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50241303(CHEMBL245317 | ethyl hydrogen (1-(3-(1-methyl-7-ox...)
Affinity DataIC50:  156nMAssay Description:Inhibition of phosphodiesterase 1 from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073698(5-methyl-2-octyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  160nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50111900(4-[4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50146545(2-[6-(3,4-Dimethoxy-benzylamino)-7-ethyl-7H-purin-...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50073699(2-ethyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50:  295nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059047((6aR,9aS)-2-Propyl-5,6a,7,8,9,9a-hexahydro-5-methy...)
Affinity DataIC50:  350nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  561nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  739nMAssay Description:Inhibition of phosphodiesterase 1 from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of bovine aorta PDE1 (Phosphodiesterase 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059028((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-cyc...)
Affinity DataIC50:  1.25E+3nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50421642(CHEMBL516604)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117701(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117712(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50475621(CHEMBL371434)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of bovine aorta PDE1 (Phosphodiesterase 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15297(CHEMBL34431 | Cilostamide | N-Cyclohexyl-N-methyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14769(6-(3,4-Dimethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117707(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117703(3-But-3-enyl-8-[2-ethoxy-5-(4-methyl-piperazine-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117704(3-Cyclopropylmethyl-8-[2-ethoxy-5-(4-methyl-pipera...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117710(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50475612(CHEMBL201169)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475614(CHEMBL201249)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475620(CHEMBL372819)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475624(CHEMBL202832)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475615(CHEMBL425927)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50009071(6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50141581(4-(3-Chloro-4-methoxy-benzylamino)-7-trifluorometh...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphodiesterase 1 of bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50475617(CHEMBL433988)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475616(CHEMBL199878)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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