Compile Data Set for Download or QSAR
maximum 50k data
Found 2154 of ic50 data for polymerid = 4998,50007716,50007728,5039,7025,7431,7622,8207,9974
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM110191(3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)propenone...)
Affinity DataIC50:  0.0130nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as diphenolase activity incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM110192(3-(2,4-Dihydroxyphenyl)-1-(furan-2-yl)propenone (1...)
Affinity DataIC50:  0.0433nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as diphenolase activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50356191(CHEMBL193804)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activity preincubated for 20 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50608336(CHEMBL517832)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610779(CHEMBL4475728)
Affinity DataIC50:  0.0680nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as a substrate by UV-2450 spectrophotometeric assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610794(CHEMBL5286802)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610795(CHEMBL5289108)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610793(CHEMBL5286240)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50276368(CHEMBL4128371)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610775(CHEMBL5277673)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTyrosinase(Homo sapiens (Human))TBA
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM110192(3-(2,4-Dihydroxyphenyl)-1-(furan-2-yl)propenone (1...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610778(CHEMBL4562624)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as a substrate by UV-2450 spectrophotometeric assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610783(CHEMBL4064477)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTyrosinase(Homo sapiens (Human))TBA
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  0.613nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50045000((NFLX)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosinase(Homo sapiens (Human))TBA
LigandPNGBDBM50241367(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-((2S,4R,5...)
Affinity DataIC50:  0.762nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosinase(Homo sapiens (Human))TBA
LigandPNGBDBM50217942(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chr...)
Affinity DataIC50:  0.856nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosinase(Homo sapiens (Human))TBA
LigandPNGBDBM50378581(NICOTIFLOROSIDE)
Affinity DataIC50:  0.908nMAssay Description:Inhibition of tyrosinase (unknown origin) using DOPA as substrate incubated for 15 min by spectrophotometer assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM110191(3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)propenone...)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as monophenolase activity incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50208612((-)-kurarinone | (2S)-2-(2,4-dihydroxyphenyl)-7-hy...)
Affinity DataIC50:  0.960nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosinase(Homo sapiens (Human))TBA
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human his tagged tyrosinase expressed in HEK293 cells using L-DOPA as substrate by HTS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50366824(Avelox | MOXIFLOXACIN | Moxifl-oxacin)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50234121(CHEMBL4069921)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated with compound for 20 mins measured after 1 minMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610789(CHEMBL5284672)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610764(CHEMBL5282064)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50356191(CHEMBL193804)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate assessed as diphenolase activity preincubated for 20 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610786(CHEMBL5285434)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610774(CHEMBL4291894)
Affinity DataIC50:  2nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 10 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50608335(CHEMBL479477)
Affinity DataIC50:  2nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometer assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610769(CHEMBL5270388)
Affinity DataIC50:  2nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activityMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610780(CHEMBL5271322)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activity incubated for 10 mins by microplate reader analysi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610766(CHEMBL5273863)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 5 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50568146(CHEMBL1481541)
Affinity DataIC50:  3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610785(CHEMBL5270398)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50276368(CHEMBL4128371)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50276368(CHEMBL4128371)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610768(CHEMBL5266436)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50021467(CHEMBL3289933)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610788(CHEMBL5276716)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50021465(CHEMBL3289931)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610782(CHEMBL5273032)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as diphenolase activity by microplate reader analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610767(CHEMBL5268456)
Affinity DataIC50:  9nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610769(CHEMBL5270388)
Affinity DataIC50:  9nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as diphenolase activityMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610792(CHEMBL5266001)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 5 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50610763(CHEMBL5272877)
Affinity DataIC50:  10nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 20 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50339940(4-(Benzo[d]thiazol-2-yl)benzene-1,3-diol | CHEMBL1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))TBA
LigandPNGBDBM50021417(CHEMBL3289924)
Affinity DataIC50:  10nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
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