Compile Data Set for Download or QSAR
maximum 50k data
Found 273 of ki data for polymerid = 4998,50007716,50007728,5039,7025,7431,7622,8207,9974
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50269559(2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKi:  0.610nM ΔG°:  -12.8kcal/moleT: 2°CAssay Description:Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50134709(CHEMBL3747057)
Affinity DataKi:  1.5nMAssay Description:Time dependent inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate measured every 30 secs by Morrison and Walsh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50502237(CHEMBL4470451)
Affinity DataKi:  1.60nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataKi:  2.40nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate assessed as inhibition constant incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50568146(CHEMBL1481541)
Affinity DataKi:  3.10nMAssay Description:Noncompetitive inhibition of mushroom tyrosinase assessed as dissociation constant using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50610781(CHEMBL5277261)
Affinity DataKi:  4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as a substrate assessed as inhibition constant incubated for 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50134709(CHEMBL3747057)
Affinity DataKi:  19nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated for 5 to 60 mins by Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50330795(2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one ...)
Affinity DataKi:  20nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50569812(CHEMBL4869068)
Affinity DataKi:  40nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50343137(CHEMBL1770313 | Cyclomorusin | Cycolmorusin, 2)
Affinity DataKi:  46.4nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50254430(CHEMBL468906 | broussonin C)
Affinity DataKi:  48.5nMAssay Description:Inhibition of mushroom tyrosinase by kinetic based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM91591(Mormin, 1)
Affinity DataKi:  49.2nM ΔG°:  -10.1kcal/moleT: 2°CAssay Description:Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50330794(2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone | ...)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50569806(CHEMBL4865646)
Affinity DataKi:  70nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50610790(CHEMBL5287587)
Affinity DataKi:  76nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant preincubated with compound for 15 mins by microplate read...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50242015(CHEMBL518543 | Kuwanon C, 4 | kuwanon C)
Affinity DataKi:  80.5nM ΔG°:  -9.83kcal/moleT: 2°CAssay Description:Mushroom tyrosinase using either L-DOPA or L-tyrosine as substrate. In spectrophotometric experiments, enzyme activity was monitored by dopachrome f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50569801(CHEMBL4867662)
Affinity DataKi:  90nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50134709(CHEMBL3747057)
Affinity DataKi:  130nMAssay Description:Competitive inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate preincubated for 5 to 60 mins by Lineweaver-Burk and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50134710(CHEMBL3745886)
Affinity DataKi:  151nMAssay Description:Time dependent inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate measured every 30 secs by Morrison and Walsh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50251001(CHEMBL457677 | Kazinol F)
Affinity DataKi:  181nMAssay Description:Inhibition of mushroom tyrosinase by kinetic based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50304605(5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione...)
Affinity DataKi:  190nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50254430(CHEMBL468906 | broussonin C)
Affinity DataKi:  230nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot based kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataKi:  250nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50254430(CHEMBL468906 | broussonin C)
Affinity DataKi:  290nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using as L-DOPA substrate by Lineweaver-Burk plot based kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University of Tehran

LigandPNGBDBM233016(p-Xylidine-bis(dithiocarbamate) sodium salt (II))
Affinity DataKi:  290nM ΔG°:  -8.97kcal/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50240041(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataKi:  350nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataKi:  350nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataKi:  350nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataKi:  374nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50251001(CHEMBL457677 | Kazinol F)
Affinity DataKi:  410nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot based kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50485276(CHEMBL233375)
Affinity DataKi:  413nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50495308(CHEMBL3103546)
Affinity DataKi:  480nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins with substrate followed by enzyme addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50320717(5,5'-methylenebis(1,3,4-thiadiazole-2(3H)-thione) ...)
Affinity DataKi:  490nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50304602(5-(4-(tert-butyldimethylsilyloxy)phenyl)-1,3,4-thi...)
Affinity DataKi:  530nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataKi:  567nMAssay Description:Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50495305(CHEMBL3103544)
Affinity DataKi:  630nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins with substrate followed by enzyme addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University of Tehran

LigandPNGBDBM233016(p-Xylidine-bis(dithiocarbamate) sodium salt (II))
Affinity DataKi:  640nM ΔG°:  -8.50kcal/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50339940(4-(Benzo[d]thiazol-2-yl)benzene-1,3-diol | CHEMBL1...)
Affinity DataKi:  673nMAssay Description:Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50442881(SILYBIN A)
Affinity DataKi:  700nMAssay Description:Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50442881(SILYBIN A)
Affinity DataKi:  700nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50499815(CHEMBL3739883)
Affinity DataKi:  700nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50251001(CHEMBL457677 | Kazinol F)
Affinity DataKi:  770nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using as L-DOPA substrate by Lineweaver-Burk plot based kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50324036(2-[5-(2,4-Dimethoxy-phenyl)-1H-pyrazol-3-yl]-6-(2-...)
Affinity DataKi:  840nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataKi:  840nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 20 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50495309(Flemichin D)
Affinity DataKi:  860nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins with substrate followed by enzyme addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50254431(5'-(2-methylbut-3-en-2-yl)-6''-(3-methylbut-2-enyl...)
Affinity DataKi:  870nMAssay Description:Inhibition of mushroom tyrosinase by kinetic based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University of Tehran

LigandPNGBDBM233016(p-Xylidine-bis(dithiocarbamate) sodium salt (II))
Affinity DataKi:  950nM ΔG°:  -8.54kcal/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Gyeongsang National University

LigandPNGBDBM50324036(2-[5-(2,4-Dimethoxy-phenyl)-1H-pyrazol-3-yl]-6-(2-...)
Affinity DataKi:  960nMAssay Description:Inhibition of mashroom tyrosinase assessed as oxidation of L-DOPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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