Compile Data Set for Download or QSAR
Found 10 of affinity data for UniProtKB/TrEMBL: Q9JIP4
TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50574566(CHEMBL4855581)
Show SMILES OC(=O)c1cc2cc(ccc2n1Cc1ccc(cc1)C(O)=O)S(=O)(=O)N(Cc1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C31H26N2O6S/c34-30(35)25-13-11-24(12-14-25)21-33-28-16-15-27(17-26(28)18-29(33)31(36)37)40(38,39)32(19-22-7-3-1-4-8-22)20-23-9-5-2-6-10-23/h1-18H,19-21H2,(H,34,35)(H,36,37)
Affinity DataIC50: 250nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
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TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50574568(CHEBI:82411 | CHEMBL3184128)
Show SMILES [Na+].[Na+].CCN(Cc1cccc(c1)S([O-])(=O)=O)c1ccc(cc1)C(=C1C=CC(C=C1)=[N+](CC)Cc1cccc(c1)S([O-])(=O)=O)c1ccccc1S([O-])(=O)=O
Show InChI InChI=1S/C37H36N2O9S3.2Na/c1-3-38(25-27-9-7-11-33(23-27)49(40,41)42)31-19-15-29(16-20-31)37(35-13-5-6-14-36(35)51(46,47)48)30-17-21-32(22-18-30)39(4-2)26-28-10-8-12-34(24-28)50(43,44)45;;/h5-24H,3-4,25-26H2,1-2H3,(H2-,40,41,42,43,44,45,46,47,48);;/q;2*+1/p-2
Affinity DataIC50: 270nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
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TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50574567(CHEMBL4847247)
Show SMILES OC(=O)c1cc2cc(ccc2n1Cc1ccc(cc1)C(O)=O)S(=O)(=O)NCc1ccc(cc1)C(O)=O
Show InChI InChI=1S/C25H20N2O8S/c28-23(29)17-5-1-15(2-6-17)13-26-36(34,35)20-9-10-21-19(11-20)12-22(25(32)33)27(21)14-16-3-7-18(8-4-16)24(30)31/h1-12,26H,13-14H2,(H,28,29)(H,30,31)(H,32,33)
Affinity DataIC50: 800nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
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TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50574565(CHEMBL4858078)
Show SMILES OC(=O)c1cc2cc(ccc2n1Cc1ccc(cc1)C(O)=O)[N+]([O-])=O
Show InChI InChI=1S/C17H12N2O6/c20-16(21)11-3-1-10(2-4-11)9-18-14-6-5-13(19(24)25)7-12(14)8-15(18)17(22)23/h1-8H,9H2,(H,20,21)(H,22,23)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
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TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50247012(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)
Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O
Show InChI InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40)/t21-,23-,24-,27+,30+,31-,32-,33+,34+/m0/s1
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50574563(CHEMBL4862099)
Show SMILES OC(=O)c1cn(CCCc2ccccc2)c2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C18H16N2O4/c21-18(22)16-12-19(10-4-7-13-5-2-1-3-6-13)17-9-8-14(20(23)24)11-15(16)17/h1-3,5-6,8-9,11-12H,4,7,10H2,(H,21,22)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
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TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50574564(CHEMBL4849404)
Show SMILES OC(=O)c1cc2cc(ccc2n1CCCc1ccccc1)[N+]([O-])=O
Show InChI InChI=1S/C18H16N2O4/c21-18(22)17-12-14-11-15(20(23)24)8-9-16(14)19(17)10-4-7-13-5-2-1-3-6-13/h1-3,5-6,8-9,11-12H,4,7,10H2,(H,21,22)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
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TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50574562(CHEMBL4873114)
Show SMILES OC(=O)c1cn(Cc2ccccc2)c2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C16H12N2O4/c19-16(20)14-10-17(9-11-4-2-1-3-5-11)15-7-6-12(18(21)22)8-13(14)15/h1-8,10H,9H2,(H,19,20)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
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TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50485599(5-NITRO-2-PHENYLPROPYLAMINOBENZOIC ACID [NPPB] | C...)
Show SMILES OC(=O)c1cc(ccc1NCCCc1ccccc1)[N+]([O-])=O
Show InChI InChI=1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPannexin-1(Mus musculus)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +...More data for this Ligand-Target Pair
In DepthDetails PubMed