Compile Data Set for Download or QSAR
Found 6 of affinity data for UniProtKB/TrEMBL: Q96NZ9
TargetProline-rich acidic protein 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574991(CHEMBL4854774)
Show SMILES CC(=O)Nc1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F
Show InChI InChI=1S/C43H41FN8O5/c1-24-17-25(2)47-41(55)35(24)23-46-40(54)33-20-30(21-37(26(33)3)48-27(4)53)29-10-12-39(45-22-29)51-13-15-52(16-14-51)43(57)34-18-28(9-11-36(34)44)19-38-31-7-5-6-8-32(31)42(56)50-49-38/h5-12,17-18,20-22H,13-16,19,23H2,1-4H3,(H,46,54)(H,47,55)(H,48,53)(H,50,56)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetProline-rich acidic protein 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Show SMILES COC1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F
Show InChI InChI=1S/C22H22FN3O3/c1-29-15-8-10-26(11-9-15)22(28)18-12-14(6-7-19(18)23)13-20-16-4-2-3-5-17(16)21(27)25-24-20/h2-7,12,15H,8-11,13H2,1H3,(H,25,27)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
TargetProline-rich acidic protein 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574992(CHEMBL4850135)
Show SMILES CCC(=O)Nc1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F
Show InChI InChI=1S/C44H43FN8O5/c1-5-40(54)49-37-22-30(21-33(27(37)4)41(55)47-24-35-25(2)18-26(3)48-42(35)56)29-11-13-39(46-23-29)52-14-16-53(17-15-52)44(58)34-19-28(10-12-36(34)45)20-38-31-8-6-7-9-32(31)43(57)51-50-38/h6-13,18-19,21-23H,5,14-17,20,24H2,1-4H3,(H,47,55)(H,48,56)(H,49,54)(H,51,57)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetProline-rich acidic protein 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574989(CHEMBL4856941)
Show SMILES CCN(C(=O)CC)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F
Show InChI InChI=1S/C46H47FN8O5/c1-6-42(56)55(7-2)40-24-32(23-35(29(40)5)43(57)49-26-37-27(3)20-28(4)50-44(37)58)31-13-15-41(48-25-31)53-16-18-54(19-17-53)46(60)36-21-30(12-14-38(36)47)22-39-33-10-8-9-11-34(33)45(59)52-51-39/h8-15,20-21,23-25H,6-7,16-19,22,26H2,1-5H3,(H,49,57)(H,50,58)(H,52,59)
Affinity DataIC50: 14nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetProline-rich acidic protein 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574993(CHEMBL4869660)
Show SMILES CC(C)CC(=O)Nc1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F
Show InChI InChI=1S/C46H47FN8O5/c1-26(2)18-42(56)51-39-23-32(22-35(29(39)5)43(57)49-25-37-27(3)19-28(4)50-44(37)58)31-11-13-41(48-24-31)54-14-16-55(17-15-54)46(60)36-20-30(10-12-38(36)47)21-40-33-8-6-7-9-34(33)45(59)53-52-40/h6-13,19-20,22-24,26H,14-18,21,25H2,1-5H3,(H,49,57)(H,50,58)(H,51,56)(H,53,59)
Affinity DataIC50: 15nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetProline-rich acidic protein 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574990(CHEMBL4849327)
Show SMILES CCN(C(=O)C(C)=C)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(nc1)N1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F
Show InChI InChI=1S/C47H47FN8O5/c1-7-56(46(60)27(2)3)41-24-33(23-36(30(41)6)43(57)50-26-38-28(4)20-29(5)51-44(38)58)32-13-15-42(49-25-32)54-16-18-55(19-17-54)47(61)37-21-31(12-14-39(37)48)22-40-34-10-8-9-11-35(34)45(59)53-52-40/h8-15,20-21,23-25H,2,7,16-19,22,26H2,1,3-6H3,(H,50,57)(H,51,58)(H,53,59)
Affinity DataIC50: 19nMAssay Description:Inhibition of PRAP1 (unknown origin) by HT universal chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid