TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Agonist activity at recombinant human GABAA receptor alpha1beta1gamma2L expressed in Xenopus laevis oocytes incubated for 30 secs by electrophysiolog...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 980nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 1.92E+3nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 9.00E+3nMAssay Description:Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GABAB1b receptor expressed in RBL cells by microplate analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta1(S290N)gamma2S mutant receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as i...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta1(S290N)gamma2S mutant receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as i...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: 1.94E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: 3.27E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Affinity DataEC50: 3.80E+4nMAssay Description:Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.80E+4nMAssay Description:Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: 4.00E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40E+4nMAssay Description:Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
Affinity DataEC50: 4.70E+4nMAssay Description:Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
Affinity DataEC50: 5.10E+4nMAssay Description:Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: 5.74E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: 9.10E+4nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Affinity DataEC50: 9.80E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta1gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit beta-1/beta-2(Homo sapiens (Human))
University Of Mississippi
Curated by ChEMBL
University Of Mississippi
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B1/B2 receptor expressed in HEK293/Cre-luc cells assessed as inhibition of forskolin-stimulated cAMP accumulation afte...More data for this Ligand-Target Pair
Affinity DataEC50: 1.48E+5nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta1gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair
Affinity DataEC50: 2.71E+5nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta1gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair
