Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ec50 for UniProtKB: Q8IWU9
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243617((S)-2-Amino-3-(4-{2-amino-6-[2,2,2-trifluoro-1-(3'...)
Affinity DataEC50:  560nMAssay Description:Inhibition of TPH2 in human BON cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243619((S) -2-amino-3-[4-(2-amino-6-[2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  750nMAssay Description:Inhibition of TPH2 in human BON cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243618((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  800nMAssay Description:Inhibition of TPH2 in human BON cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243655((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3...)
Affinity DataEC50:  1.19E+3nMAssay Description:Inhibition of TPH2 in human BON cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed