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Found 305 of ic50 for UniProtKB: P80299
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50066843(CHEMBL3401636)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50066840(CHEMBL3401639)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50581728(CHEMBL5093683)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50581727(CHEMBL5084744)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50066841(CHEMBL3401638)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50454599(CHEMBL4216368)
Affinity DataIC50:  1nMAssay Description:Inhibition of soluble epoxide in rat brain microsomes using CMNPC substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50264113(CHEMBL4099452)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant rat sEH using MNPC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50100519(CHEMBL3327067 | US10377744, Compound No. 2391)
Affinity DataIC50: <1.30nMAssay Description:Inhibition of rat soluble epoxide hydrolase using [3H]-t-DPPO as a substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50454598(CHEMBL4215208)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of soluble epoxide in rat brain microsomes using CMNPC substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50417987(CHEMBL1672132)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of rat soluble epoxide hydrolase in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50264152(CHEMBL4072536)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant rat sEH using MNPC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50100518(CHEMBL3327064 | US10377744, Compound No. 2389)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of rat soluble epoxide hydrolase using [3H]-t-DPPO as a substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50560757(CHEMBL4784283)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50435764(CHEMBL2392692)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat soluble epoxide hydrolase using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde incubated for 10 mins prior ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50310794(CHEMBL1080973 | N-(2,4-dichlorobenzyl)-3-methyl-3-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50310797(3-methyl-3-phenyl-N-(4-(pyridin-2-yl)benzyl)piperi...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50310822(CHEMBL1078754 | methyl 3-(1-(4-chlorophenylcarbamo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50417983(CHEMBL1672128)
Affinity DataIC50:  3.02nMAssay Description:Inhibition of rat soluble epoxide hydrolase in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446768(CHEMBL3114595)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50066844(CHEMBL3401635)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50445769(CHEMBL3104615)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of rat recombinant sEH expressed in baculovirus infected insect Sf9 cells using cyano(6-methoxynaphthalen-2-yl)methyl trans-[(3-phenyloxir...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50560743(CHEMBL4759592)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446774(CHEMBL3114618)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50066845(CHEMBL3401634)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of recombinant rat soluble epoxide hydrolase assessed as increase in fluorescence intensity by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50268440(2-(2,4-dichlorophenyl)-1-(6-(methylsulfonyl)spiro[...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50310818(3-methyl-3-phenyl-N-((1S,2R)-2-phenylcyclopropyl)p...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50302475(CHEMBL567491 | N-(3,3-diphenylpropyl)-1-(2-ethoxye...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446754(CHEMBL3114609)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50441467(CHEMBL2436573)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446771(CHEMBL3114592)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50302461(CHEMBL567703 | N-((4'-(methylsulfonyl)biphenyl-4-y...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50441468(CHEMBL2436564)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50441469(CHEMBL2436586)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50297413(CHEMBL560537 | N-(3,3-diphenyl-propyl)-nicotinamid...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50310787(CHEMBL1079360 | N-(4-chlorophenyl)-3-methyl-3-phen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50310799(CHEMBL1078265 | N-(4-chlorophenethyl)-3-methyl-3-p...)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM25738(1-adamantan-1-yl-3-{5-[2-(2-ethoxyethoxy)ethoxy]pe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446763(CHEMBL3114600)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446764(CHEMBL3114599)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50441470(CHEMBL2436574)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446775(CHEMBL3114617)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50305643(4-(1-(2,4-dichlorobenzylcarbamoyl)piperidin-4-ylox...)
Affinity DataIC50:  5.30nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50441471(CHEMBL2436572)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50441472(CHEMBL2436578)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50446761(CHEMBL3114602)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50310800(3-methyl-3-phenyl-N-(3-(pyridin-3-yl)propyl)piperi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50297400((S)-4-Cyano-N-[3-(4-fluorophenyl)-3-(4-methanesulf...)
Affinity DataIC50:  6nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50297414(CHEMBL556234 | N-[3-(4-Fluorophenyl)-3-(4-methanes...)
Affinity DataIC50:  6nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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