Compile Data Set for Download or QSAR
Report error Found 20 of ic50 for UniProtKB: Q64729
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015639BDBM50015639(CHEMBL3260567 | USRE47141, Example 2)
Affinity DataIC50: 12nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252542BDBM50252542(3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...)
Affinity DataIC50: 44nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382318BDBM50382318(CHEMBL2024685)
Affinity DataIC50: 44nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382325BDBM50382325(CHEMBL2024693)
Affinity DataIC50: 46nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382324BDBM50382324(CHEMBL2024691)
Affinity DataIC50: 47nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 282825BDBM282825(6-(4-(3-chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of TGFbetaR1 in TGFbeta-stimulated mouse NIH3T3 cells assessed as reduction in SMAD3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382321BDBM50382321(CHEMBL2024688)
Affinity DataIC50: 61nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382323BDBM50382323(CHEMBL2024690)
Affinity DataIC50: 73nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298220BDBM50298220(2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50: 77nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015640BDBM50015640(LY-2157299 | GALUNISERTIB)
Affinity DataIC50: 100nMAssay Description:Inhibition of ALK5 in mouse 4T1 cells assessed as inhibition of TGFbeta1-induced luciferase activity after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262079BDBM50262079(LDN-193189 | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo...)
Affinity DataIC50: 117nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382319BDBM50382319(CHEMBL2024686)
Affinity DataIC50: 135nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382317BDBM50382317(CHEMBL2024684)
Affinity DataIC50: 211nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 102619BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50: 236nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382322BDBM50382322(CHEMBL2024689)
Affinity DataIC50: 274nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382320BDBM50382320(CHEMBL2024687)
Affinity DataIC50: 695nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382326BDBM50382326(CHEMBL2024692)
Affinity DataIC50: 708nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36354BDBM36354(DMH1 | 4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 5.97E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262685BDBM50262685(CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...)
Affinity DataIC50: 7.83E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 102618BDBM102618(LDN-212854)
Affinity DataIC50: 9.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2013
Entry Details Article
PubMed