Compile Data Set for Download or QSAR
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Found 654 of ic50 for UniProtKB: P43116
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640273(2-Cyclobutoxy-4-{6-[2-(7-methoxy-5-methyl-2,3-dihy...)
Affinity DataIC50:  1nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639887(3-Ethoxy-5-{6-[2-(6-methoxy-4-methyl-benzofuran-5-...)
Affinity DataIC50:  1nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639918(3-Ethoxy-5-{6-[2-(7-ethoxy-2,3-dihydro-benzo[1,4]d...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640100(2-Ethoxy-4-{6-[2-(6-methoxy-4-methyl-benzofuran-5-...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639883(3-Ethoxy-5-{6-[2-(6-methoxy-benzo[b]thiophen-5-yl)...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640277(4-{6-[2-(7-Methoxy-5-methyl-2,3-dihydro-benzo[1,4]...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM50092618(CHEMBL3586362)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H]PGE2 from human recombinant prostanoid EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639891(3-Ethoxy-5-{6-[2-(6-methoxy-benzofuran-5-yl)-ethyl...)
Affinity DataIC50:  3nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640016(4-{6-[2-(7-Ethoxy-2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50:  4nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639897(4-{6-[2-(6-Methoxy-benzo[b]thiophen-5-yl)-ethylami...)
Affinity DataIC50:  4nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640272(2-Ethoxy-4-{6-[2-(7-methoxy-5-methyl-2,3-dihydro-b...)
Affinity DataIC50:  5nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640087(2-Cyclobutoxy-4-{6-[2-(6-methoxy-4-methyl-benzofur...)
Affinity DataIC50:  5nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640005(2-Ethoxy-4-{6-[2-(6-ethoxy-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  6nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640244(3-Ethoxy-5-{6-[2-(4-fluoro-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  6nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639981((2-Ethoxy-4-{6-[2-(6-methoxy-4-methyl-benzofuran-5...)
Affinity DataIC50:  6nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640305((4-{6-[2-(7-Methoxy-5-methyl-2,3-dihydro-benzo[1,4...)
Affinity DataIC50:  7nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640282(4-{6-[2-(7-Fluoro-6-methoxy-benzo[b]thiophen-5-yl)...)
Affinity DataIC50:  7nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639913(3-Ethoxy-5-{6-[2-(6-methyl-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  8nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639928(3-Ethoxy-5-{6-[2-(6-methoxy-benzo[1,3]dioxol-5-yl)...)
Affinity DataIC50:  8nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM50092615(CHEMBL3586361)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639880(3-Ethoxy-5-{6-[2-(3-methoxy-1-methyl-naphthalen-2-...)
Affinity DataIC50:  8nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640246(4-{6-[2-(4-Fluoro-benzo[b]thiophen-5-yl)-ethylamin...)
Affinity DataIC50:  9nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM50092618(CHEMBL3586362)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640309(2-Isopropoxy-4-{6-[2-(7-methoxy-5-methyl-2,3-dihyd...)
Affinity DataIC50:  10nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM50506546(Omidenepag | UR-7276)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]prostaglandin E2 from human EP2 receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639899(3-Ethoxy-5-{6-[2-(4-methyl-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  11nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639988(2-Ethoxy-4-{6-[2-(6-methoxy-benzo[b]thiophen-5-yl)...)
Affinity DataIC50:  12nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639932((2-Ethoxy-4-{6-[2-(6-ethoxy-benzo[b]thiophen-5-yl)...)
Affinity DataIC50:  12nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639886(3-Ethoxy-5-{6-[2-(1-methyl-naphthalen-2-yl)-ethyla...)
Affinity DataIC50:  12nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640072(4-{6-[2-(6-Methoxy-benzofuran-5-yl)-ethylamino]-py...)
Affinity DataIC50:  12nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639942(2-Cyclobutoxy-4-{6-[2-(6-methoxy-benzo[b]thiophen-...)
Affinity DataIC50:  12nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639983(3-Ethoxy-5-{6-[2-(7-fluoro-4-methyl-3,4-dihydro-2H...)
Affinity DataIC50:  13nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639978((2-Ethoxy-4-{6-[2-(7-ethoxy-2,3-dihydro-benzo[1,4]...)
Affinity DataIC50:  13nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640156(4-{6-[2-(6-Methoxy-benzo[1,3]dioxol-5-yl)-ethylami...)
Affinity DataIC50:  14nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639909(3-Ethoxy-5-{6-[2-(7-methyl-2,3-dihydro-benzo[1,4]d...)
Affinity DataIC50:  14nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639892(3-Ethoxy-5-{6-[2-(6-fluoro-benzofuran-5-yl)-ethyla...)
Affinity DataIC50:  15nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640324(2-Cyclopropoxy-4-{6-[2-(7-ethoxy-2,3-dihydro-benzo...)
Affinity DataIC50:  16nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640037(2-Ethylsulfanyl-4-{6-[2-(6-methoxy-benzofuran-5-yl...)
Affinity DataIC50:  16nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640304((4-{6-[2-(7-Ethoxy-2,3-dihydro-benzo[1,4]dioxin-6-...)
Affinity DataIC50:  17nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640069(4-{6-[2-(6-Methyl-benzo[b]thiophen-5-yl)-ethylamin...)
Affinity DataIC50:  18nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639938(4-{6-[2-(3-Methoxy-1-methyl-naphthalen-2-yl)-ethyl...)
Affinity DataIC50:  18nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639902(3-Ethoxy-5-{6-[2-(3-ethoxy-naphthalen-2-yl)-ethyla...)
Affinity DataIC50:  19nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639906(5-{6-[2-(3-Cyano-benzo[b]thiophen-5-yl)-ethylamino...)
Affinity DataIC50:  19nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639905(3-Ethoxy-5-{6-[2-(7-methoxy-2,3-dihydro-benzo[1,4]...)
Affinity DataIC50:  19nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640140(2-Ethoxy-4-{6-[2-(7-ethoxy-2,3-dihydro-benzo[1,4]d...)
Affinity DataIC50:  20nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM50092760(CHEMBL3586312)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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