Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair