Compile Data Set for Download or QSAR
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Found 207 Enz. Inhib. hit(s) with all data for entry = 50037061
TargetP2Y purinoceptor 12(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118225(ARL 69931MX | Adenosine triphosphate derivative | ...)
Affinity DataIC50:  0.400nMAssay Description:The compound was evaluated for antagonist activity against platelet P2Y purinoceptor 12 (P2Y12)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  84nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 3 (P2X3 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50:  210nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  400nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 2 (P2X2) receptor 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118245(CHEMBL133572 | MG 40-3)
Affinity DataIC50: <1.00E+3nMAssay Description:The compound was evaluated for antagonistic activity at P2Y purinoceptor 1 (P2Y1) from guinea pig taenia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118214(CHEMBL133930 | DIDS)
Affinity DataIC50:  1.00E+3nMAssay Description:The compound was evaluated for inhibition of P2X purinoceptor in PC12 bladder cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118245(CHEMBL133572 | MG 40-3)
Affinity DataIC50:  1.60E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) like receptor from rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118215(CHEMBL1628528 | Ip5I)
Affinity DataIC50:  2.80E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X2) receptor 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118211(Acid Blue 129 | CHEMBL133576 | cid_23675739 | sodi...)
Affinity DataIC50:  3.00E+3nMAssay Description:The compound was evaluated for antagonistic activity at P2Y purinoceptor 1 (P2Y1) from guinea pig taenia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118237(CHEMBL130059 | Uniblue A)
Affinity DataIC50:  7.50E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) from rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118218(CHEMBL131271 | Disodium 1-amino-4-[4-(4,6-dichloro...)
Affinity DataIC50:  8.80E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) like receptor from rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118231(CHEMBL134193 | Cibachron Blue 3GA)
Affinity DataIC50:  9.60E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) from rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118234(CHEMBL129904 | MRS 2160)
Affinity DataIC50:  9.60E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) receptor from rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118214(CHEMBL133930 | DIDS)
Affinity DataIC50:  1.10E+4nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor; range 11-54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50:  2.85E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 3 (P2X3 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118215(CHEMBL1628528 | Ip5I)
Affinity DataIC50: >3.00E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 2 (P2X2) at 30 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118214(CHEMBL133930 | DIDS)
Affinity DataIC50:  3.50E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 2(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 2 (P2X2) at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda...)
Affinity DataIC50:  5.83E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X2) 10 uM, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118214(CHEMBL133930 | DIDS)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366943(TRYPAN BLUE)
Affinity DataIC50:  1.71E+5nMAssay Description:The compound was evaluated for antagonistic activity against P2Y purinoceptor 2 (P2Y2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50026893(CHEMBL3085531)
Affinity DataEC50: >1.00E+5nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 4 (P2Y4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataEC50:  9.20E+4nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118232(2-MeSATP | ATP, 2-meS | CHEMBL336208)
Affinity DataEC50:  8nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  7.80E+5nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118233(2'-deoxyadenosine 5'-(tetrahydrogen triphosphate) ...)
Affinity DataEC50:  1.90E+4nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50368125(ADENOSINE DIPHOSPHATE | ADP)
Affinity DataEC50:  8.00E+3nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118221(9H-purine derivative | CHEMBL132722 | DIPHOSPHOMET...)
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118217(ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE | ATP-g...)
Affinity DataEC50:  1.30E+3nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118240(((2R,3S,4R,5R)-5-(6-amino-2-(hexylthio)-9H-purin-9...)
Affinity DataEC50:  4.80nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50029031(1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...)
Affinity DataEC50: >1.00E+4nMAssay Description:Evaluated for antagonist activity agonist phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118221(9H-purine derivative | CHEMBL132722 | DIPHOSPHOMET...)
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118227(CHEMBL133051 | MRS 2268)
Affinity DataEC50:  155nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataEC50:  3.00E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 3 (P2X2) at 10 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50370141(TNP-ATP)
Affinity DataEC50:  1.52E+4nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 3 (P2X3 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118235(Brilliant Blue | CHEMBL423337)
Affinity DataEC50:  0.100nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50026893(CHEMBL3085531)
Affinity DataEC50: >1.00E+5nMAssay Description:The compound was evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 6 (P2Y6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)
Affinity DataEC50:  330nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076474(CHEMBL416252 | Phosphoric acid mono-[5-(6-amino-pu...)
Affinity DataEC50:  3nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataEC50: >1.00E+4nMAssay Description:Evaluated for antagonistactivity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  2.80E+3nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118243(CHEMBL334823 | MRS 2191)
Affinity DataEC50:  4.40nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50370142(CHEMBL133463)
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataEC50:  34nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50026893(CHEMBL3085531)
Affinity DataEC50:  52nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Rattus norvegicus)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50026893(CHEMBL3085531)
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against phospholipase C coupled rat P2Y purinoceptor 12 (P2Y12)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242(((2R,3S,4R,5R)-5-(6-amino-2-(methylthio)-9H-purin-...)
Affinity DataEC50:  6nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of turkey erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50026893(CHEMBL3085531)
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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