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Found 38 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 369
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264118(3-(4-(4-(4-(5-oxo-1,6-naphthyridin-6(5H)-yl)phenyl...)
Affinity DataIC50:  0.230nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264120(3-(4-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...)
Affinity DataIC50:  0.530nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264122(3-(4-(4-(4-(2-oxopyrazin-1(2H)-yl)phenyl)piperazin...)
Affinity DataIC50:  0.800nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264119(3-(3-(4-(4-(5-oxo-1,6-naphthyridin-6(5H)-yl)phenyl...)
Affinity DataIC50:  0.930nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264098(3-(3-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataIC50:  0.980nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264113(3-(3-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264124(3-(4-(4-(4-(2-oxotetrahydropyrimidin-1(2H)-yl)phen...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264112(3-(4-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264125(3-(3-(4-(4-(2-oxotetrahydropyrimidin-1(2H)-yl)phen...)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264101(3-(5-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataIC50:  1.40nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264097(1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264104(3-(4-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataIC50:  1.70nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264011(3-(4-(4-(4-(2-oxopiperidin-1-yl)phenyl)piperazin-1...)
Affinity DataIC50:  1.80nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264123(3-(3-(4-(4-(2-oxopyrazin-1(2H)-yl)phenyl)piperazin...)
Affinity DataIC50:  1.80nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264109(3-(3-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataIC50:  1.80nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264106(3-(2-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataIC50:  2nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264093(3-(4-(4-(4-(3-oxomorpholino)phenyl)piperazin-1-yl)...)
Affinity DataIC50:  2.20nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264115(3-(5-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataIC50:  2.20nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264100(3-(2-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataIC50:  2.60nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264107(3-(5-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataIC50:  3.60nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264024(1-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...)
Affinity DataIC50:  4.20nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264121(3-(3-(4-(4-(4-oxofuro[3,2-c]pyridin-5 (4H)-yl)phen...)
Affinity DataIC50:  4.20nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM263988(1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataIC50:  4.30nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264117(3-(3-(4-(4-(1-oxoisoquinolin-2(1H)-yl)phenyl)piper...)
Affinity DataIC50:  4.30nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264111(3-(5-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataIC50:  5.5nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264114(3-(2-(4-(4-(3,5-difluoro-2-oxopyridin-1(2H)-yl)phe...)
Affinity DataIC50:  5.5nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264092(4-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataIC50:  6.30nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264099(1-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...)
Affinity DataIC50:  7.10nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264094(4-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...)
Affinity DataIC50:  7.30nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264108(3-(4-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataIC50:  7.40nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264105(3-(3-(4-(4-(4-methyl-2-oxopyridin-1(2H)-yl)phenyl)...)
Affinity DataIC50:  7.5nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264096(3-(4-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl)piperazin...)
Affinity DataIC50:  8nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264091(3-(3-(4-(4-(2-oxopiperidin-1-yl)phenyl)piperazin-1...)
Affinity DataIC50:  8.5nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264095(3-(3-(4-(4-(3-oxomorpholino)phenyl)piperazin-1-yl)...)
Affinity DataIC50:  10nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264116(3-(4-(4-(4-(1-oxoisoquinolin-2(1H)-yl)phenyl)piper...)
Affinity DataIC50:  10nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264110(3-(2-(4-(4-(4-methoxy-2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataIC50:  12nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264103(3-(1-hydroxy-3-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataIC50:  170nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264102(3-(1-hydroxy-4-(4-(4-(2-oxopyridin-1(2H)-yl)phenyl...)
Affinity DataIC50:  330nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent