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Found 35 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50012101
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114725(CHEMBL314512 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114703(CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114718(But-3-enoic acid [2-(5-methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114732(1-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-3...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114716(CHEMBL329263 | N-[2-(2-Benzyl-5-methoxy-benzofuran...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114707(But-3-enoic acid [2-(2-benzyl-5-methoxy-benzofuran...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114701(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114712(CHEMBL96859 | N-[2-(2-Benzyl-5-methoxy-benzofuran-...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114720(But-2-enoic acid [2-(5-methoxy-2-phenyl-benzofuran...)
Affinity DataKi:  0.210nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114714(CHEMBL94607 | N-{2-[2-(3-Chloro-benzyl)-5-methoxy-...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114730(CHEMBL95166 | N-{2-[2-(3-Fluoro-benzyl)-5-methoxy-...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114704(CHEMBL33549 | N-(2-(5-methoxy-2-(3-methoxybenzyl)b...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114702(CHEMBL329960 | N-{2-[5-Methoxy-2-(2-methoxy-benzyl...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50037242(CHEMBL323332 | N-(2-(5-methoxybenzofuran-3-yl)ethy...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114709(1-[2-(2-Benzyl-5-methoxy-benzofuran-3-yl)-ethyl]-3...)
Affinity DataKi:  0.350nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114721(CHEMBL328617 | N-[2-(2-Benzyl-5-methoxy-benzofuran...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114715(CHEMBL317742 | N-{2-[5-Methoxy-2-(4-methoxy-benzyl...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114719(CHEMBL96548 | N-[2-(2-Benzyl-5-methoxy-benzofuran-...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114700(CHEMBL314947 | N-{2-[5-Methoxy-2-(3-trifluoromethy...)
Affinity DataKi:  1.17nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114713(CHEMBL98074 | N-{2-[5-Methoxy-2-(3-phenyl-propyl)-...)
Affinity DataKi:  1.52nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114729(CHEMBL96420 | Furan-2-carboxylic acid [2-(5-methox...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114710(CHEMBL329299 | N-[2-(2-Cyclohexylmethyl-5-methoxy-...)
Affinity DataKi:  2.49nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114706(CHEMBL96916 | N-{2-[5-Methoxy-2-(3-methoxy-benzyl)...)
Affinity DataKi:  2.76nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114727(CHEMBL315653 | N-[2-(2-Benzyl-5-hexyloxy-benzofura...)
Affinity DataKi:  3.21nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114726(CHEMBL94745 | N-[2-(5-Methoxy-2-pyridin-3-ylmethyl...)
Affinity DataKi:  3.53nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114717(CHEMBL96333 | N-[2-(2-Benzyl-5-ethyl-benzofuran-3-...)
Affinity DataKi:  8.25nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114724(CHEMBL94919 | N-[2-(2-Benzyl-5-pentyloxy-benzofura...)
Affinity DataKi:  9.64nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114705(CHEMBL440144 | N-[2-(2-Benzyl-benzofuran-3-yl)-eth...)
Affinity DataKi:  10.6nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114728(CHEMBL96562 | N-{2-[2-(2,6-Dichloro-benzyl)-5-meth...)
Affinity DataKi:  12.8nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114723(CHEMBL96778 | N-{2-[5-Ethyl-2-(3-methoxy-benzyl)-b...)
Affinity DataKi:  17nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114722(CHEMBL445117 | N-{2-[2-(3-Methoxy-benzyl)-benzofur...)
Affinity DataKi:  18.6nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114731(CHEMBL96173 | Furan-2-carboxylic acid [2-(2-benzyl...)
Affinity DataKi:  36.7nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114708(CHEMBL91813 | N-[2-(2-Benzyl-5-hydroxy-benzofuran-...)
Affinity DataKi:  79.9nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114711(CHEMBL327864 | N-{2-[2-(3,5-Bis-trifluoromethyl-be...)
Affinity DataKi:  340nMAssay Description:Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed