TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataKi: 211nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of MST2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Inhibition of recombinant MST2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MST2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MST2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human MST2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of STK3 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human MST2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human MST2 using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant MST2 using Ser/Thr peptide 7 substrate after 45 mins by Z-Lyte assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli using myelin basic protein as substrat...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <40nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <40nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <40nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <40nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human MST2 (2 to end residues) using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by scin...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli using myelin basic protein as substrat...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Sanford Burnham Prebys Medical Discovery Institute
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair