Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 6040
TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105226BDBM105226(US8580800, 2)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105231BDBM105231(US8580800, 23)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105227BDBM105227(US8580800, 4)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105232BDBM105232(US8580800, 27)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105230BDBM105230(US8580800, 17)
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105229BDBM105229(US8580800, 9)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105233BDBM105233(US8580800, 31)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105225BDBM105225(US8580800, 1)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 105228BDBM105228(US8580800, 8)
Affinity DataIC50: 32nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent