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Found 33 Enz. Inhib. hit(s) with all data for entry = 50008621
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.430nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075360(3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-p...)
Affinity DataKi:  1.30nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075362(3-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,...)
Affinity DataKi:  1.80nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075357(2-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,...)
Affinity DataKi:  2nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50450987(CHEMBL2112913)
Affinity DataKi:  6.5nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075363(2-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  7nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50450988(CHEMBL2112912)
Affinity DataKi:  10nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075359(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-1...)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50450988(CHEMBL2112912)
Affinity DataKi:  21nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075365(2-[2-(4-Styryl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]...)
Affinity DataKi:  25nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075356(3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  26nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075365(2-[2-(4-Styryl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]...)
Affinity DataKi:  30nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50450988(CHEMBL2112912)
Affinity DataKi:  34nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075359(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-1...)
Affinity DataKi:  50nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075364(2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  59nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075363(2-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  170nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50450987(CHEMBL2112913)
Affinity DataKi:  180nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075357(2-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,...)
Affinity DataKi:  200nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075357(2-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,...)
Affinity DataKi:  250nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50450987(CHEMBL2112913)
Affinity DataKi:  280nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075356(3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  530nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075364(2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  600nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075363(2-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  640nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075359(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-1...)
Affinity DataKi:  800nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075356(3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  900nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  960nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075362(3-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,...)
Affinity DataKi:  1.10E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075364(2-(1H-Pyrrolo[2,3-b]pyridin-2-ylmethyl)-1,2,3,4-te...)
Affinity DataKi:  1.10E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075365(2-[2-(4-Styryl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]...)
Affinity DataKi:  1.30E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075362(3-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,...)
Affinity DataKi:  1.30E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075360(3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-p...)
Affinity DataKi: >1.50E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  2.30E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075360(3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-p...)
Affinity DataKi:  3.90E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed