Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50010977
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100934(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100925(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100932(N-{2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100924(N-Hydroxy-N-[1-(4'-methoxy-biphenyl-4-yloxymethyl)...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100922(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100938(N-[1-(4'-Butyl-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100931(N-Hydroxy-N-[1-(4'-methyl-biphenyl-4-yloxymethyl)-...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100930(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100929(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50: 42nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100926(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 48nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(3,4,4-tr...)
Affinity DataIC50: 58nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100936(N-Hydroxy-N-[2-(3,4,4-trimethyl-2,5-dioxo-imidazol...)
Affinity DataIC50: 61nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100921(N-[1-(4-Furan-2-yl-phenoxymethyl)-2-(3,4,4-trimeth...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100920(N-[1-(Biphenyl-4-yloxymethyl)-2-(3,4,4-trimethyl-2...)
Affinity DataIC50: 89nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50: 120nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100935(N-Hydroxy-N-[1-(4-thiophen-2-yl-phenoxymethyl)-2-(...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100924(N-Hydroxy-N-[1-(4'-methoxy-biphenyl-4-yloxymethyl)...)
Affinity DataIC50: 440nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100930(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 840nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100934(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100920(N-[1-(Biphenyl-4-yloxymethyl)-2-(3,4,4-trimethyl-2...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100928(N-[1-(3'-Cyano-biphenyl-4-yloxymethyl)-2-(3,4,4-tr...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100921(N-[1-(4-Furan-2-yl-phenoxymethyl)-2-(3,4,4-trimeth...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100931(N-Hydroxy-N-[1-(4'-methyl-biphenyl-4-yloxymethyl)-...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(3,4,4-tr...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100935(N-Hydroxy-N-[1-(4-thiophen-2-yl-phenoxymethyl)-2-(...)
Affinity DataIC50: 3.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100926(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 4.90E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100922(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 8.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100929(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100938(N-[1-(4'-Butyl-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100928(N-[1-(3'-Cyano-biphenyl-4-yloxymethyl)-2-(3,4,4-tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100937(N-[1-(4'-Cyano-biphenyl-3-yloxymethyl)-2-(3,4,4-tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100925(N-[2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100937(N-[1-(4'-Cyano-biphenyl-3-yloxymethyl)-2-(3,4,4-tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100936(N-Hydroxy-N-[2-(3,4,4-trimethyl-2,5-dioxo-imidazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100933(N-Hydroxy-N-[1-(4-pyridin-3-yl-phenoxymethyl)-2-(3...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100933(N-Hydroxy-N-[1-(4-pyridin-3-yl-phenoxymethyl)-2-(3...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100932(N-{2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed