Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50037319
TargetPurine nucleoside phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50195587(CHEMBL218291 | CHEMBL1213652 | 1,4-DIDEOXY-4-AZA-1...)
Affinity DataKi:  0.0560nMAssay Description:Inhibitory activity of compound against human purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKi:  0.166nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148131(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-prop...)
Affinity DataKi:  0.214nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36494(CHEMBL554965 | ImmA-Et)
Affinity DataKi:  0.266nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKi:  0.576nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148132(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-m-to...)
Affinity DataKi:  0.628nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148134(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-p-to...)
Affinity DataKi:  0.640nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50140797((2S,3S,4R,5S)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataKi:  1nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148127(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-phen...)
Affinity DataKi:  1nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148132(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-m-to...)
Affinity DataKi:  1.39nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148130(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(4-f...)
Affinity DataKi:  2nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148135(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(2-f...)
Affinity DataKi:  3.20nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148127(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-phen...)
Affinity DataKi:  3.60nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148131(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-prop...)
Affinity DataKi:  4nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148134(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-p-to...)
Affinity DataKi:  4.40nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148141(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(3-c...)
Affinity DataKi:  6.40nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148130(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(4-f...)
Affinity DataKi:  6.40nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36494(CHEMBL554965 | ImmA-Et)
Affinity DataKi:  9.20nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148133(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(2-h...)
Affinity DataKi:  14nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148135(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(2-f...)
Affinity DataKi:  20nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM36495(CHEMBL554642 | ImmA-Bn)
Affinity DataKi:  26nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50140797((2S,3S,4R,5S)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataKi:  26nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148142(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-prop...)
Affinity DataKi:  44nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148133(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(2-h...)
Affinity DataKi:  56nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148129(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(nap...)
Affinity DataKi:  90nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148128(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-meth...)
Affinity DataKi:  134nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Human)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50148139(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-meth...)
Affinity DataKi:  720nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed