Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50016164
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM18031(CHEMBL193816 | Ketopiperazine-based inhibitor, 11)
Affinity DataIC50: 7nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165800(7-((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phen...)
Affinity DataIC50: 17nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165796(1-{4-[3-(2-METHOXY-BENZYLOXY)-PROPOXY]-PHENYL}-6-(...)
Affinity DataIC50: 23nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165802((S)-6-[1-(2-Hydroxy-ethyl)-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 33nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165804((S)-6-[1-(3-Hydroxy-propyl)-1,2,3,4-tetrahydro-qui...)
Affinity DataIC50: 35nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM18029(CHEMBL372416 | (6R)-6-({[1-(3-hydroxypropyl)-1,2,3...)
Affinity DataIC50: 37nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17966((6R)-1-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phe...)
Affinity DataIC50: 54nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165803((R)-6-[1-(2-Hydroxy-ethyl)-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 64nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165798((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 66nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165799((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 120nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165797((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 820nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165801((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 860nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed