Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50016894
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174939(CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174932(CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174934(CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174929(CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174935(CHEMBL371688 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12229(AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174937(CHEMBL198946 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174930(1-(4-(3-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174938(CHEMBL425209 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174928(CHEMBL200231 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174929(CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174932(CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174940(CHEMBL197339 | N-(5-chloro-2-methoxypyridin-4-yl)-...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174931(CHEMBL198752 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174935(CHEMBL371688 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174934(CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174939(CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174941(CHEMBL197186 | N-(5-chloro-2-methoxypyridin-4-yl)-...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174938(CHEMBL425209 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174937(CHEMBL198946 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174929(CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174932(CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12229(AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)
Affinity DataIC50:  280nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174940(CHEMBL197339 | N-(5-chloro-2-methoxypyridin-4-yl)-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12229(AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174941(CHEMBL197186 | N-(5-chloro-2-methoxypyridin-4-yl)-...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174935(CHEMBL371688 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174931(CHEMBL198752 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  680nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174934(CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174928(CHEMBL200231 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174930(1-(4-(3-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174938(CHEMBL425209 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174937(CHEMBL198946 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174939(CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed