Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50016894
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174939(N-(3-chloro-6-methoxypyridin-2-yl)-7-(3-morpholino...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174932(N-(2-chloro-5-methoxypyridin-3-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174934(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174929(N-(2-chloro-5-methoxypyridin-3-yl)-7-(3-morpholino...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174935(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12229(N-(2-chloro-5-methoxyphenyl)-7-[3-(morpholin-4-yl)...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174937(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174930(1-(4-(3-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174938(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174928(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174932(N-(2-chloro-5-methoxypyridin-3-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12232(N-(2-chloro-5-methoxyphenyl)-7-[3-(morpholin-4-yl)...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174929(N-(2-chloro-5-methoxypyridin-3-yl)-7-(3-morpholino...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174940(N-(5-chloro-2-methoxypyridin-4-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12232(N-(2-chloro-5-methoxyphenyl)-7-[3-(morpholin-4-yl)...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174931(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174934(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174935(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174939(N-(3-chloro-6-methoxypyridin-2-yl)-7-(3-morpholino...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174941(N-(5-chloro-2-methoxypyridin-4-yl)-7-(3-morpholino...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174937(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174938(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174929(N-(2-chloro-5-methoxypyridin-3-yl)-7-(3-morpholino...)
Affinity DataIC50: 140nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12232(N-(2-chloro-5-methoxyphenyl)-7-[3-(morpholin-4-yl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174932(N-(2-chloro-5-methoxypyridin-3-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12229(N-(2-chloro-5-methoxyphenyl)-7-[3-(morpholin-4-yl)...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)
Affinity DataIC50: 280nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174940(N-(5-chloro-2-methoxypyridin-4-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174941(N-(5-chloro-2-methoxypyridin-4-yl)-7-(3-morpholino...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM12229(N-(2-chloro-5-methoxyphenyl)-7-[3-(morpholin-4-yl)...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174935(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 570nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174931(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 680nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174934(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174928(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174930(1-(4-(3-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174938(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174937(N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174939(N-(3-chloro-6-methoxypyridin-2-yl)-7-(3-morpholino...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed