Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50017191
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178827BDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178827BDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178843BDBM50178843((3R)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178830BDBM50178830(N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178832BDBM50178832(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)-te...)
Affinity DataIC50: 7nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178836BDBM50178836(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)-te...)
Affinity DataIC50: 8nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178846BDBM50178846(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 9nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178842BDBM50178842((3S)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178838BDBM50178838(1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178839BDBM50178839(cis-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 15nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178848BDBM50178848(N-(4-fluorophenyl)-4-(2-(4-fluorophenylamino)pyrid...)
Affinity DataIC50: 17nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178837BDBM50178837(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)fur...)
Affinity DataIC50: 18nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178829BDBM50178829(3-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50: 20nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178841BDBM50178841(4-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50: 32nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178840BDBM50178840(N-(2-fluorophenyl)-4-(2-(2-fluorophenylamino)pyrid...)
Affinity DataIC50: 32nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178844BDBM50178844(5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 33nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178846BDBM50178846(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 37nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178839BDBM50178839(cis-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178837BDBM50178837(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)fur...)
Affinity DataIC50: 42nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178825BDBM50178825(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 44nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178827BDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 48nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178827BDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 48nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178843BDBM50178843((3R)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178843BDBM50178843((3R)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50: 74nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178846BDBM50178846(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 82nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178838BDBM50178838(1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl...)
Affinity DataIC50: 85nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178839BDBM50178839(cis-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 88nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178841BDBM50178841(4-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50: 106nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178834BDBM50178834(N1-(4-(2-(2-aminophenylamino)pyridin-4-yl)pyridin-...)
Affinity DataIC50: 108nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178836BDBM50178836(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)-te...)
Affinity DataIC50: 122nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178842BDBM50178842((3S)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50: 125nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178830BDBM50178830(N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-...)
Affinity DataIC50: 152nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178842BDBM50178842((3S)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50: 162nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178838BDBM50178838(1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl...)
Affinity DataIC50: 171nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178828BDBM50178828(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)nic...)
Affinity DataIC50: 175nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178832BDBM50178832(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)-te...)
Affinity DataIC50: 180nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178830BDBM50178830(N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-...)
Affinity DataIC50: 199nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178849BDBM50178849(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 207nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178825BDBM50178825(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 219nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178847BDBM50178847(N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}...)
Affinity DataIC50: 235nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178836BDBM50178836(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)-te...)
Affinity DataIC50: 251nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178844BDBM50178844(5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50: 261nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178832BDBM50178832(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)-te...)
Affinity DataIC50: 384nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178829BDBM50178829(3-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50: 451nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178826BDBM50178826(N-(2-methoxyphenyl)-4-(2-(2-methoxyphenylamino)pyr...)
Affinity DataIC50: 528nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178827BDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 581nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178827BDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50: 581nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178831BDBM50178831(4-(2-(o-toluidino)pyridin-4-yl)-N-o-tolylpyridin-2...)
Affinity DataIC50: 652nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178835BDBM50178835(N-(2-ethoxyphenyl)-4-(2-(2-ethoxyphenylamino)pyrid...)
Affinity DataIC50: 693nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50178828BDBM50178828(N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)nic...)
Affinity DataIC50: 780nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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