Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 1206
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10007(4-[6-Methoxybenzofuran-2-yl)-1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10013(4-[(6-hydroxy-1-benzofuran-2-yl)(1H-1,2,4-triazol-...)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10005(1-[(4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10000(6-Methoxybenzofuran-2-yl-(4-fluorophenyl)-3-pyridy...)
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10001((4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10014(2-[(4-nitrophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1...)
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10009(1-[(6-methoxy-1-benzofuran-2-yl)(4-methylphenyl)me...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10003(1-[(6-methoxy-1-benzofuran-2-yl)(4-methoxyphenyl)m...)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10006(1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10010(1-[(6-Methoxybenzofuran-2-yl)-(4-trifluoromethylph...)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10002((6-methoxy-1-benzofuran-2-yl)(4-methoxyphenyl)pyri...)
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10008(1-[(6-methoxy-1-benzofuran-2-yl)(4-nitrophenyl)met...)
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10015(NSC719344 | arimidex | 2-[3-(1-cyano-1-methylethyl...)
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10011(1-[(6-Methoxybenzofuran-2-yl)-(4-ethylphenyl)methy...)
Affinity DataIC50: 1.23E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Cardiff University

LigandPNGBDBM10012(2-[(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-...)
Affinity DataIC50: 1.46E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2006
Entry Details Article
PubMed