Compile Data Set for Download or QSAR
Report error Found 132 Enz. Inhib. hit(s) with all data for entry = 50017405
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181881(N-[2'-methoxy-4'-(3-morpholin-4-ylpropyl)biphenyl-...)
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181875(4-((R)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181869(4-((R)-5-dimethylamino-1-phenylsulfanylmethylpenty...)
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181889(4-((R)-5-amino-1-phenylsulfanylmethylpentylamino)-...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21400(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181872(4-((R)-4-Dimethylamino-1-phenylsulfanylmethylbutyl...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181891(4-((R)-5-amino-1-phenylsulfanylmethylpentylamino)-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181888(N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-4-((R)-3...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181877(4-((R)-5-dimethylamino-1-phenylsulfanylmethylpenty...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181882((R)-3-(4-{[2'-methoxy-4'-(3-morpholin-4-ylpropyl)b...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181880(4-((R)-4-dimethylamino-1-phenylsulfanylmethylbutyl...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181885((R)-3-{4-[4-(4,4-dimethylpiperidin-1-yl)benzoylsul...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181878(N-[2'-methoxy-4'-(3-morpholin-4-ylpropyl)biphenyl-...)
Affinity DataKi:  10nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181873(N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-3-nitro-...)
Affinity DataKi:  19nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181868(N-[4'-(3-hydroxypropyl)-2'-methoxybiphenyl-4-carbo...)
Affinity DataKi:  22nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181889(4-((R)-5-amino-1-phenylsulfanylmethylpentylamino)-...)
Affinity DataKi:  30nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181876(N-(4'-fluoro-biphenyl-4-carbonyl)-3-nitro-4-(2-phe...)
Affinity DataKi:  36nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181883(3-{2-methoxy-4'-[3-nitro-4-(2-phenylsulfanylethyla...)
Affinity DataKi:  39nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181888(N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-4-((R)-3...)
Affinity DataKi:  55nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181874(N-[2'-methoxy-4'-(3-morpholin-4-yl-3-oxopropyl)bip...)
Affinity DataKi:  58nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181869(4-((R)-5-dimethylamino-1-phenylsulfanylmethylpenty...)
Affinity DataKi:  59nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21400(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  67nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181889(4-((R)-5-amino-1-phenylsulfanylmethylpentylamino)-...)
Affinity DataKi:  70nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181872(4-((R)-4-Dimethylamino-1-phenylsulfanylmethylbutyl...)
Affinity DataKi:  71nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181877(4-((R)-5-dimethylamino-1-phenylsulfanylmethylpenty...)
Affinity DataKi:  73nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181894(N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-4-((S)-3...)
Affinity DataKi:  75nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181885((R)-3-{4-[4-(4,4-dimethylpiperidin-1-yl)benzoylsul...)
Affinity DataKi:  75nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181880(4-((R)-4-dimethylamino-1-phenylsulfanylmethylbutyl...)
Affinity DataKi:  92nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181870(N-[4'-(3-dimethylaminopropyl)-2'-methoxybiphenyl-4...)
Affinity DataKi:  106nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181875(4-((R)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi:  116nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181882((R)-3-(4-{[2'-methoxy-4'-(3-morpholin-4-ylpropyl)b...)
Affinity DataKi:  121nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181876(N-(4'-fluoro-biphenyl-4-carbonyl)-3-nitro-4-(2-phe...)
Affinity DataIC50: 122nMAssay Description:Inhibitory activity against Bcl-XL in presence of alpha-1 acid glycoprotein from 1% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181875(4-((R)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi:  148nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181881(N-[2'-methoxy-4'-(3-morpholin-4-ylpropyl)biphenyl-...)
Affinity DataKi:  165nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181877(4-((R)-5-dimethylamino-1-phenylsulfanylmethylpenty...)
Affinity DataKi:  174nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181873(N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-3-nitro-...)
Affinity DataKi:  192nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181869(4-((R)-5-dimethylamino-1-phenylsulfanylmethylpenty...)
Affinity DataKi:  215nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181891(4-((R)-5-amino-1-phenylsulfanylmethylpentylamino)-...)
Affinity DataKi:  231nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181893(4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi:  250nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181879(2-{2-methoxy-4'-[3-nitro-4-(2-phenylsulfanylethyla...)
Affinity DataKi:  251nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181867(4-((S)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataKi:  252nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181891(4-((R)-5-amino-1-phenylsulfanylmethylpentylamino)-...)
Affinity DataKi:  256nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181871(4-{4-[3-nitro-4-(2-phenylsulfanylethylamino)benzen...)
Affinity DataKi:  294nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181872(4-((R)-4-Dimethylamino-1-phenylsulfanylmethylbutyl...)
Affinity DataKi:  317nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21400(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  360nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181874(N-[2'-methoxy-4'-(3-morpholin-4-yl-3-oxopropyl)bip...)
Affinity DataKi:  366nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181888(N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-4-((R)-3...)
Affinity DataEC50:  368nMAssay Description:Activity towards mouse FL5.12 cell line transfected with Bcl-XL in presence of gelatinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181881(N-[2'-methoxy-4'-(3-morpholin-4-ylpropyl)biphenyl-...)
Affinity DataEC50:  382nMAssay Description:Activity towards mouse FL5.12 cell line transfected with Bcl-XL in presence of gelatinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181892(4-{4-[3-nitro-4-(2-phenylsulfanylethylamino)benzen...)
Affinity DataKi:  396nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181875(4-((R)-3-dimethylamino-1-phenylsulfanylmethylpropy...)
Affinity DataEC50:  399nMAssay Description:Activity towards mouse FL5.12 cell line transfected with Bcl-XL in presence of gelatinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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