Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50037753
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188063(3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile |...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188043(1-(2-(3-chlorophenyl)-1-phenylethyl)piperazine | C...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188056(3-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | CHEMB...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188060(1-(1-phenyl-2-(2-(trifluoromethyl)phenyl)ethyl)pip...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50124566(2-[(2-Ethoxy-phenoxy)-phenyl-methyl]-morpholine | ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188051(1-(1-phenyl-2-o-tolylethyl)piperazine | CHEMBL2100...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188062(1-(1-phenyl-2-(2-(trifluoromethoxy)phenyl)ethyl)pi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188045(1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine | C...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188053(1-(1-phenyl-2-(3-(trifluoromethyl)phenyl)ethyl)pip...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188059(1-(1,2-diphenylethyl)piperazine | CHEMBL214237)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188056(3-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | CHEMB...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188052(1-(2-(2-bromophenyl)-1-phenylethyl)piperazine | CH...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188054(1-(2-(2-ethylphenyl)-1-phenylethyl)piperazine | CH...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188045(1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine | C...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188048((-)-1-(2-(2-methoxyphenyl)-1-phenylethyl)piperazin...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188048((-)-1-(2-(2-methoxyphenyl)-1-phenylethyl)piperazin...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188044(1-(2-(3-methoxyphenyl)-1-phenylethyl)piperazine | ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188060(1-(1-phenyl-2-(2-(trifluoromethyl)phenyl)ethyl)pip...)
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188055(1-(1-phenyl-2-(2-propoxyphenyl)ethyl)piperazine | ...)
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188052(1-(2-(2-bromophenyl)-1-phenylethyl)piperazine | CH...)
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188062(1-(1-phenyl-2-(2-(trifluoromethoxy)phenyl)ethyl)pi...)
Affinity DataIC50: 38nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188046(1-(1-phenyl-2-(2-(2,2,2-trifluoroethoxy)phenyl)eth...)
Affinity DataIC50: 38nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188059(1-(1,2-diphenylethyl)piperazine | CHEMBL214237)
Affinity DataIC50: 39nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188043(1-(2-(3-chlorophenyl)-1-phenylethyl)piperazine | C...)
Affinity DataIC50: 54nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188046(1-(1-phenyl-2-(2-(2,2,2-trifluoroethoxy)phenyl)eth...)
Affinity DataIC50: 61nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188054(1-(2-(2-ethylphenyl)-1-phenylethyl)piperazine | CH...)
Affinity DataIC50: 72nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188050(2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile |...)
Affinity DataIC50: 73nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188050(2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile |...)
Affinity DataIC50: 87nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188051(1-(1-phenyl-2-o-tolylethyl)piperazine | CHEMBL2100...)
Affinity DataIC50: 90nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188044(1-(2-(3-methoxyphenyl)-1-phenylethyl)piperazine | ...)
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188047(3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzamide | CH...)
Affinity DataIC50: 210nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188057(1-(2-(2-(methylsulfonyl)phenyl)-1-phenylethyl)pipe...)
Affinity DataIC50: 270nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188063(3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile |...)
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188053(1-(1-phenyl-2-(3-(trifluoromethyl)phenyl)ethyl)pip...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188061(2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzamide | CH...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50188047(3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzamide | CH...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188061(2-(2-phenyl-2-(piperazin-1-yl)ethyl)benzamide | CH...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188057(1-(2-(2-(methylsulfonyl)phenyl)-1-phenylethyl)pipe...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50124566(2-[(2-Ethoxy-phenoxy)-phenyl-methyl]-morpholine | ...)
Affinity DataIC50: 590nMAssay Description:Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataIC50: 870nMAssay Description:Inhibition of DA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188049(CHEMBL213287 | CHEMBL534942 | 1-(2-(2-chlorophenyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of DA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188056(3-(2-phenyl-2-(piperazin-1-yl)ethyl)phenol | CHEMB...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of DA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188045(1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine | C...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of DA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188046(1-(1-phenyl-2-(2-(2,2,2-trifluoroethoxy)phenyl)eth...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of DA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 58 total ) | Next | Last >>
Jump to: