Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 1539
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11976(5-chloro-2-(5-{[(4E)-3,8-dioxo-5,16-dithia-2,7-dia...)
Affinity DataKi:  800nM ΔG°:  -35.0kJ/mole IC50:  1.10E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11983(3-(4-chlorophenyl)-1-{4-[(5-ethyl-1,3,4-thiadiazol...)
Affinity DataKi:  900nM ΔG°:  -34.7kJ/mole IC50:  4.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11996(2-[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]acetic ac...)
Affinity DataKi:  900nM ΔG°:  -34.7kJ/mole IC50:  7.60E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, the concentrations of inhibitor that caused 50% inhibition of enzymati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11989(2-chloro-5-[(4Z)-3-methyl-5-oxo-4-{[4-(propan-2-yl...)
Affinity DataKi:  900nM ΔG°:  -34.7kJ/mole IC50:  8.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11980((5Z)-5-[(2,4-dihydroxyphenyl)methylidene]-2-sulfan...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.2kJ/mole IC50:  3.70E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11985(4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...)
Affinity DataKi:  1.50E+3nM ΔG°:  -33.5kJ/mole IC50:  3.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11977(5-bromo-2-(5-{[(4Z)-1-(3-carboxyphenyl)-5-oxo-3-(t...)
Affinity DataKi:  1.60E+3nM ΔG°:  -33.3kJ/mole IC50:  1.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11994(2-{[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]sulfanyl...)
Affinity DataKi:  1.60E+3nM ΔG°:  -33.3kJ/mole IC50:  2.90E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, the concentrations of inhibitor that caused 50% inhibition of enzymati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11991(8-{N-[4-(2,3-dihydro-1,3-thiazol-2-ylsulfamoyl)phe...)
Affinity DataKi:  1.80E+3nM ΔG°:  -33.0kJ/mole IC50:  8.70E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11993(2-chloro-5-[(4Z)-4-{[5-(4-chlorophenyl)furan-2-yl]...)
Affinity DataKi:  2.10E+3nM ΔG°:  -32.6kJ/mole IC50:  1.00E+4nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11979(5-[(3-carboxy-4-hydroxyphenyl)methyl]-2-hydroxyben...)
Affinity DataKi:  2.40E+3nM ΔG°:  -32.3kJ/mole IC50:  2.90E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11984(2-chloro-4-{5-[N-(3-cyano-4,5,6,7-tetrahydro-1-ben...)
Affinity DataKi:  2.40E+3nM ΔG°:  -32.3kJ/mole IC50:  5.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11981(2-chloro-5-{[(4Z)-4-{[4-(methylsulfanyl)phenyl]met...)
Affinity DataKi:  2.50E+3nM ΔG°:  -32.2kJ/mole IC50:  3.30E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11978((1E,6E)-4-(1,3-dithian-2-ylidene)-1,7-bis(furan-2-...)
Affinity DataKi:  2.70E+3nM ΔG°:  -32.0kJ/mole IC50:  3.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11982(2-{[(2-amino-2-carboxyethyl)sulfanyl]methyl}-5-phe...)
Affinity DataKi:  2.90E+3nM ΔG°:  -31.8kJ/mole IC50:  4.10E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11987(2-hydroxy-5-(5-{[(5Z)-2-imino-4-oxo-3-(1,3-thiazol...)
Affinity DataKi:  3.10E+3nM ΔG°:  -31.7kJ/mole IC50:  4.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11986(3-[(5E)-5-[(3-bromo-4-methoxyphenyl)methylidene]-4...)
Affinity DataKi:  3.30E+3nM ΔG°:  -31.5kJ/mole IC50:  4.70E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11988((5Z)-5-(1,3-benzothiazol-2-ylimino)-1-(4-sulfophen...)
Affinity DataKi:  4.20E+3nM ΔG°:  -30.9kJ/mole IC50:  9.20E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11990(4-(5-{[(3E)-5-cyano-2-hydroxy-4-methyl-6-oxo-3,6-d...)
Affinity DataKi:  5.40E+3nM ΔG°:  -30.3kJ/mole IC50:  1.08E+4nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11995(2-chloro-5-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic ac...)
Affinity DataKi:  5.60E+3nM ΔG°:  -30.2kJ/mole IC50:  6.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, the concentrations of inhibitor that caused 50% inhibition of enzymati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11992(3-(5-{[(4Z)-1-(3-chlorophenyl)-3,5-dioxopyrazolidi...)
Affinity DataKi:  7.20E+3nM ΔG°:  -29.5kJ/mole IC50:  1.39E+4nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed