Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50019268
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168825BDBM50168825(1-(3-Chloro-4-fluoro-phenyl)-3-[2-(3'-cyano-biphen...)
Affinity DataKi:  0.980nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184924BDBM50184924(N-[trans-5-(4-cyanophenyl)bicyclo[3.1.0]hex-2-yl]-...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203355BDBM50203355(3-(3-chloro-4-fluorophenyl)-1-((1R,3R,6S)-6-(3-cya...)
Affinity DataKi:  4nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203346BDBM50203346(N-(7-(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpi...)
Affinity DataKi:  6nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203352BDBM50203352(3-(3-chloro-4-fluorophenyl)-1-(7-cyano-1,2,3,4-tet...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50164243BDBM50164243((R)-1-(3'-cyanobiphenyl-4-yl)-3-(4-fluoro-3-(trifl...)
Affinity DataKi:  8.90nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203354BDBM50203354(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazi...)
Affinity DataKi:  11nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203347BDBM50203347(N-(7-(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpi...)
Affinity DataKi:  61nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203357BDBM50203357(3-(3-chloro-4-fluorophenyl)-1-(7-methoxy-1,2,3,4-t...)
Affinity DataKi:  92nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203349BDBM50203349(N-(7-(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpi...)
Affinity DataKi:  96nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241100BDBM50241100(1-(3-chloro-4-fluorophenyl)-3-{7-[(ethylcarbamoyl)...)
Affinity DataKi:  160nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203351BDBM50203351(1-(6-bromo-1,2,3,4-tetrahydronaphthalen-2-yl)-3-(3...)
Affinity DataKi:  180nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203348BDBM50203348(3-(3-chloro-4-fluorophenyl)-1-(6-methoxy-1,2,3,4-t...)
Affinity DataKi:  190nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203356BDBM50203356(1-(7-amino-1,2,3,4-tetrahydronaphthalen-2-yl)-3-(3...)
Affinity DataKi:  260nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203350BDBM50203350(3-(3-chloro-4-fluorophenyl)-1-(6-cyano-1,2,3,4-tet...)
Affinity DataKi:  340nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203358BDBM50203358(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazi...)
Affinity DataKi:  380nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203360BDBM50203360(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazi...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203353BDBM50203353(7-(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiper...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203359BDBM50203359(7-(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiper...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed