Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50038682
LigandChemical structure of BindingDB Monomer ID 50260153BDBM50260153(Octadecapeptide venom | Apamin | CHEMBL525408)
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50260153BDBM50260153(Octadecapeptide venom | Apamin | CHEMBL525408)
Affinity DataIC50: 0.168nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50263327BDBM50263327(N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2...)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]apamin from Kca2.3 channel expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50263327BDBM50263327(N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Kca2.1 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50263327BDBM50263327(N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264020BDBM50264020(TCMDC-124275 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]apamin from Kca2.3 channel expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264020BDBM50264020(TCMDC-124275 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50: 43nMAssay Description:Inhibition of Kca2.1 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50263327BDBM50263327(N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50263327BDBM50263327(N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2...)
Affinity DataIC50: 59nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50263327BDBM50263327(N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2...)
Affinity DataIC50: 59nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264020BDBM50264020(TCMDC-124275 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50: 123nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264020BDBM50264020(TCMDC-124275 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50: 290nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264020BDBM50264020(TCMDC-124275 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50: 543nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264020BDBM50264020(TCMDC-124275 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50: 543nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048403BDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048403BDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264072BDBM50264072(2-(2-(pyridin-2-ylmethyl)thiazol-4-yl)pyridine | C...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264071BDBM50264071(cid_704533 | CHEMBL452409 | N-(4-(pyridin-4-yl)thi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264070BDBM50264070(cid_704624 | CHEMBL492010 | N-(4-(pyridin-3-yl)thi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264021BDBM50264021(N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-4-amine | ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264019BDBM50264019(5-iodo-N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-2-a...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50263326BDBM50263326(3-chloro-N-(4-(pyridin-2-yl)thiazol-2-yl)-5-(trifl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264076BDBM50264076(N-(4-(pyridin-2-yl)thiazol-2-yl)pyrimidin-2-amine ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264075BDBM50264075(2-(4-(pyridin-2-yl)thiazol-2-yl)pyridine | CHEMBL5...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264074BDBM50264074(N,4-Diphenylthiazol-2-amine | CHEMBL510166)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50264073BDBM50264073(CHEMBL490592 | cid_873000 | N-phenyl-4-(pyridin-2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed