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Found 9 Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50128581'
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of recombinant human MAGL using 7-HRA as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of MAGL in mouse B16-F10 cells using 7-HRA as substrate preincubated for 60 mins followed by substrate addition measured every 2.5 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Wistar rat MAGL using 2-monooleoyl[1,2,3-3H]glycerol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of MAGL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of MAGL from Wistar rat brain using 2-monooleoyl[1,2,3-H]glycerol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of MAGL in Wistar rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  2.23E+5nMpH: 8.0Assay Description:The measurement of the ability of URB602 compound to inhibit MGL activity. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed