Compile Data Set for Download or QSAR
Report error Found 101 Enz. Inhib. hit(s) with all data for entry = 50027925
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277152((1S,2S,4R)-1,3,3-trimethyl-N-(4-methyl-3-(morpholi...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277193(4-methyl-3-(morpholinosulfonyl)-N-((1S,2S,4R)-1,3,...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277193(4-methyl-3-(morpholinosulfonyl)-N-((1S,2S,4R)-1,3,...)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277194(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277195(4-(5-(4-tert-butylthiazol-2-yl)-2-methylphenylsulf...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277307((1S,2R,4R)-1,3,3-trimethyl-N-(4-methyl-3-(morpholi...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277152((1S,2S,4R)-1,3,3-trimethyl-N-(4-methyl-3-(morpholi...)
Affinity DataEC50:  9.60nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277339(2,2,3,3-tetramethyl-N-(4-methyl-3-(morpholinosulfo...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277308(2-tert-butyl-3,3-dimethyl-N-(4-methyl-3-(morpholin...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277154(2,2-dimethyl-N-(4-methyl-3-(morpholinosulfonyl)phe...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277155(2-methyl-N-(4-methyl-3-(morpholinosulfonyl)phenyl)...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277196(4-(2-methyl-5-(2-neopentyl-2H-tetrazol-5-yl)phenyl...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277195(4-(5-(4-tert-butylthiazol-2-yl)-2-methylphenylsulf...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50239215(4-methyl-3-(morpholinosulfonyl)-N-(2,2,4,4-tetrame...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277194(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277192(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277309(3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277339(2,2,3,3-tetramethyl-N-(4-methyl-3-(morpholinosulfo...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277267(4-(5-(4-tert-butyl-1H-imidazol-2-yl)-2-methylpheny...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277153(4-methyl-3-(morpholinosulfonyl)-N-((1S,2R,4R)-1,3,...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277227(4-(5-(5-(cyclohexylmethyl)-1H-1,2,4-triazol-3-yl)-...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277309(3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277308(2-tert-butyl-3,3-dimethyl-N-(4-methyl-3-(morpholin...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277340(1-methyl-N-(4-methyl-3-(morpholinosulfonyl)phenyl)...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50239215(4-methyl-3-(morpholinosulfonyl)-N-(2,2,4,4-tetrame...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277340(1-methyl-N-(4-methyl-3-(morpholinosulfonyl)phenyl)...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277266(4-(2-methyl-5-(4-neopentyl-1H-imidazol-2-yl)phenyl...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277155(2-methyl-N-(4-methyl-3-(morpholinosulfonyl)phenyl)...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277266(4-(2-methyl-5-(4-neopentyl-1H-imidazol-2-yl)phenyl...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277153(4-methyl-3-(morpholinosulfonyl)-N-((1S,2R,4R)-1,3,...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277307((1S,2R,4R)-1,3,3-trimethyl-N-(4-methyl-3-(morpholi...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277196(4-(2-methyl-5-(2-neopentyl-2H-tetrazol-5-yl)phenyl...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277227(4-(5-(5-(cyclohexylmethyl)-1H-1,2,4-triazol-3-yl)-...)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277267(4-(5-(4-tert-butyl-1H-imidazol-2-yl)-2-methylpheny...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277269(4-(2-methyl-5-(5-neopentyl-1,2,4-oxadiazol-3-yl)ph...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277226(4-(2-methyl-5-(5-neopentyl-1H-1,2,4-triazol-3-yl)p...)
Affinity DataEC50:  64nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277269(4-(2-methyl-5-(5-neopentyl-1,2,4-oxadiazol-3-yl)ph...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277136(4-(5-(5-tert-butyl-1,2,4-oxadiazol-3-yl)-2-methylp...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277137(4-(2-methyl-5-(5-neopentyl-1H-pyrazol-3-yl)phenyls...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277136(4-(5-(5-tert-butyl-1,2,4-oxadiazol-3-yl)-2-methylp...)
Affinity DataEC50:  77nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277224(4-(5-(2-(cyclohexylmethyl)-2H-tetrazol-5-yl)-2-met...)
Affinity DataEC50:  78nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277268(4-(5-(2-tert-butyl-1H-imidazol-5-yl)-2-methylpheny...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277224(4-(5-(2-(cyclohexylmethyl)-2H-tetrazol-5-yl)-2-met...)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277226(4-(2-methyl-5-(5-neopentyl-1H-1,2,4-triazol-3-yl)p...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277305(4-(5-(5-(cyclohexylmethyl)-1H-pyrazol-3-yl)-2-meth...)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277228(4-(5-(5-tert-butyl-4H-1,2,4-triazol-3-yl)-2-methyl...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277270(4-(5-(5-(cyclohexylmethyl)-1,2,4-oxadiazol-3-yl)-2...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277343(3-chloro-N-(4-methyl-3-(morpholinosulfonyl)phenyl)...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptor by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277192(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50277137(4-(2-methyl-5-(5-neopentyl-1H-pyrazol-3-yl)phenyls...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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