Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50041717
TargetB2 bradykinin receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  0.0339nMAssay Description:Antagonist activity at human recombinant bradykinin 2 receptor expressed in CHO cells assessed as inhibition of bradykinin-induced intracellular calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  0.0490nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in CHO cells assessed as inhibition of NPS-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50049949(2-(2-{[1-(2-{2-[2-({1-[1-(2-Amino-5-guanidino-pent...)
Affinity DataEC50:  0.0490nMAssay Description:Antagonist activity at human recombinant bradykinin 2 receptor expressed in CHO cells assessed as inhibition of bradykinin-induced intracellular calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50001450(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met NH2 | ...)
Affinity DataEC50:  0.0575nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in CHO cells assessed as inhibition of NPS-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  0.282nMAssay Description:Antagonist activity at human recombinant NOP receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of N/OFQ-induced intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataEC50:  0.389nMAssay Description:Antagonist activity at human recombinant NOP receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of N/OFQ-induced intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  1.90nMAssay Description:Antagonist activity at human recombinant delta opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of DPDPE-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  2.30nMAssay Description:Antagonist activity at human recombinant kappa opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dynorphin A-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataEC50:  3nMAssay Description:Antagonist activity at human recombinant delta opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of DPDPE-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  3.5nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in CHO cells assessed as inhibition of urotensin 2-induced intracellular calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413784(UROTENSIN-II)
Affinity DataEC50:  4.10nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in CHO cells assessed as inhibition of urotensin 2-induced intracellular calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Mouse)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50412707(CHEMBL230333)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50010702(Dynorphin A (1-17) | dynorphin A | DYNORPHIN(1-17)...)
Affinity DataEC50:  6.30nMAssay Description:Antagonist activity at human recombinant kappa opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dynorphin A-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50059841(CHEMBL278789 | (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-...)
Affinity DataEC50:  10nMAssay Description:Antagonist activity at human recombinant mu opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dermorphin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  11nMAssay Description:Antagonist activity at human recombinant mu opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dermorphin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Mouse)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413779(CHEMBL500458)
Affinity DataEC50:  661nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Mouse)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413781(CHEMBL509091)
Affinity DataEC50:  794nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Mouse)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413778(CHEMBL500443)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Mouse)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413780(CHEMBL507664)
Affinity DataEC50:  2.69E+3nMAssay Description:Agonist activity at mouse NPSR expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413783(CHEMBL443719)
Affinity DataEC50:  2.82E+4nMAssay Description:Antagonist activity at human recombinant PAR2 expressed in A549 cells assessed as inhibition of SLIGKV-NH2-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandPNGBDBM50413782(CHEMBL1627325)
Affinity DataEC50:  3.16E+4nMAssay Description:Antagonist activity at human recombinant PAR2 expressed in A549 cells assessed as inhibition of SLIGKV-NH2-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed