Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50039027
TargetProthrombin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619((S)-2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)-2-hy...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human thrombin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human thrombin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619((S)-2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)-2-hy...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human tissue plasminogen activator by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human plasmin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human tissue plasminogen activator by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619((S)-2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)-2-hy...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human plasmin by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304619((S)-2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)-2-hy...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50270656(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304620(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304621((R)-2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)-2-hy...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304622(2-(1-{3-[(6-Chloronaphthalene-2-yl)sulfonyl]-2-oxo...)
Affinity DataIC50:  930nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304625(1-(4-aminopiperidin-1-yl)-3-(6-chloronaphthalen-2-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50304623(3-(6-chloronaphthalen-2-ylsulfonyl)propanoic acid ...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50378585(CHEMBL1627118)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human factor 10a by para-nitroanilide release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed