Compile Data Set for Download or QSAR
Report error Found 164 Enz. Inhib. hit(s) with all data for entry = 50031615
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316254BDBM50316254(methyl 4-(6-(4-(3-(4-(2-hydroxyethyl)phenyl)ureido...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316255BDBM50316255(Isopropyl 4-(6-(4-(3-Methylureido)phenyl)-4-morpho...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316257BDBM50316257(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35594BDBM35594(pyrazolo pyrimidine, 27)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316256BDBM50316256(isopropyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amino...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316258BDBM50316258(methyl 4-(6-{4-[(anilinocarbonyl)amino]phenyl}-4-m...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35578BDBM35578(pyrazolo pyrimidine, 10)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316253BDBM50316253(tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-py...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35591BDBM35591(pyrazolo pyrimidine, 23)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316259BDBM50316259(isopropyl 4-(6-{4-[(cyclopropylcarbamoyl)amino]phe...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35585BDBM35585(pyrazolo pyrimidine, 18)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35580BDBM35580(pyrazolo pyrimidine, 13)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316260BDBM50316260(tert-butyl 4-[6-(4-{[(2-fluoroethyl)carbamoyl]amin...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316262BDBM50316262(tert-butyl 4-(6-{4-[(cyclopropylcarbamoyl)amino]ph...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35590BDBM35590(pyrazolo pyrimidine, 22)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316261BDBM50316261(methyl 4-(4-morpholino-6-(4-(3-(4-(2-morpholinoeth...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316264BDBM50316264(tert-Butyl 4-(6-(4-(3-Methylureido)phenyl)-4-morph...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316263BDBM50316263(1-{4-[1-(1-Benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316265BDBM50316265(4-(4-morpholino-6-(4-(3-(4-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316267BDBM50316267(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316266BDBM50316266(methyl 4-(6-(4-(3-(4-(2-(4-methylpiperazin-1-yl)et...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316281BDBM50316281(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316280BDBM50316280(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35577BDBM35577(pyrazolo pyrimidine, 12)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316283BDBM50316283(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316284BDBM50316284(1-{4-[1-(1-Benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316271BDBM50316271(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35575BDBM35575(pyrazolo pyrimidine, 9)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316252BDBM50316252(methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazo...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316282BDBM50316282(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316285BDBM50316285(5-(4-Morpholino-1-phenyl-1H-pyrazolo[3,4-d]pyrimid...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316254BDBM50316254(methyl 4-(6-(4-(3-(4-(2-hydroxyethyl)phenyl)ureido...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316286BDBM50316286(Methyl{4-[1-(1-Benzylpiperidin-4-yl)-4-morpholin-4...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35580BDBM35580(pyrazolo pyrimidine, 13)
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35594BDBM35594(pyrazolo pyrimidine, 27)
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316276BDBM50316276(N-[4-(4-Morpholin-4-yl-1-phenyl-1H-pyrazolo[3,4-d]...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316287BDBM50316287(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316258BDBM50316258(methyl 4-(6-{4-[(anilinocarbonyl)amino]phenyl}-4-m...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316283BDBM50316283(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316288BDBM50316288(Methyl [4-(4-Morpholin-4-yl-1-phenyl-1H-pyrazolo[3...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316266BDBM50316266(methyl 4-(6-(4-(3-(4-(2-(4-methylpiperazin-1-yl)et...)
Affinity DataIC50: 21nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316290BDBM50316290(1-methoxy-3-(4-{4-morpholin-4-yl-1-[1-(pyridin-3-y...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316289BDBM50316289(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316279BDBM50316279(6-(1H-indol-5-yl)-4-morpholin-4-yl-1-phenyl-1H-pyr...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316268BDBM50316268(1-{4-[1-(1-benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316263BDBM50316263(1-{4-[1-(1-Benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316265BDBM50316265(4-(4-morpholino-6-(4-(3-(4-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316261BDBM50316261(methyl 4-(4-morpholino-6-(4-(3-(4-(2-morpholinoeth...)
Affinity DataIC50: 41nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35578BDBM35578(pyrazolo pyrimidine, 10)
Affinity DataIC50: 41nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50316253BDBM50316253(tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-py...)
Affinity DataIC50: 41nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
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