Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50004322
LigandPNGBDBM50059863(chaetomellic acid A | (Z)-2-Methyl-3-tetradecyl-bu...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481616(CHEMBL590127)
Affinity DataKi:  230nMAssay Description:Binding affinity to FPP site of human recombinant FTase by competitive Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481616(CHEMBL590127)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481625(CHEMBL599795)
Affinity DataKi:  260nMAssay Description:Binding affinity to FPP site of human recombinant FTase by competitive Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481615(CHEMBL590126)
Affinity DataKi:  500nMAssay Description:Binding affinity to FPP site of human recombinant FTase by competitive Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481615(CHEMBL590126)
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481632(CHEMBL599796)
Affinity DataIC50: 880nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481625(CHEMBL599795)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481616(CHEMBL590127)
Affinity DataKi:  5.60E+3nMAssay Description:Binding affinity to CaaX site of human recombinant FTase by non-competitive Michaelis-Menten analysis for enzyme-substrate-inhibitor complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481616(CHEMBL590127)
Affinity DataKi:  7.70E+3nMAssay Description:Binding affinity to CaaX site of human recombinant FTase by non-competitive Michaelis-Menten analysis for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481618(CHEMBL599797)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481617(CHEMBL590148)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481615(CHEMBL590126)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity to CaaX site of human recombinant FTase by non-competitive Michaelis-Menten analysis for enzyme-substrate-inhibitor complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481615(CHEMBL590126)
Affinity DataKi:  1.70E+4nMAssay Description:Binding affinity to CaaX site of human recombinant FTase by non-competitive Michaelis-Menten analysis for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481619(CHEMBL591827)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481629(CHEMBL586003)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481626(CHEMBL597132)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481631(CHEMBL590239)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481620(CHEMBL598573)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481621(CHEMBL598779)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481627(CHEMBL597738)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481630(CHEMBL597740)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481624(CHEMBL585242)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481622(CHEMBL597739)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481614(CHEMBL589907)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481628(CHEMBL609900)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481623(CHEMBL598777)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed