Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50031584
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315775(1-(4-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50:  9nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315769(3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-py...)
Affinity DataIC50:  32nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315776(1-(3-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50:  67nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315773(CHEMBL1090670 | N,N-dimethyl-1-(3-(4-(1-methyl-1H-...)
Affinity DataIC50:  104nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315774(CHEMBL1090508 | N,N-dimethyl-1-(4-(4-(1-methyl-1H-...)
Affinity DataIC50:  169nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315771(4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyri...)
Affinity DataIC50:  6.16E+3nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315770(4-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine | CH...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed