Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50031685
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317226BDBM50317226((2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclohexyl)me...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317215BDBM50317215((2R)-N-(adamantan-2-yl)-1-(cyclobutylmethyl)pyrrol...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317214BDBM50317214((2R)-N-(adamantan-2-yl)-1-(2-methylpropyl)pyrrolid...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317213BDBM50317213((2R)-N-(adamantan-2-yl)-1-(cyclopentylmethyl)pyrro...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317220BDBM50317220((2R)-N-(adamantan-2-yl)-1-[(4-cyanophenyl)methyl]p...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317221BDBM50317221((2R)-N-(adamantan-2-yl)-1-[(3-cyanophenyl)methyl]p...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317216BDBM50317216((2R)-N-(adamantan-2-yl)-1-(cyclohexylmethyl)pyrrol...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317219BDBM50317219((2R)-N-(adamantan-2-yl)-1-[(4-chlorophenyl)methyl]...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317218BDBM50317218((2R)-N-(adamantan-2-yl)-1-(3,3,3-trifluoropropyl)p...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317217BDBM50317217((2R)-N-(adamantan-2-yl)-1-(2,2,2-trifluoroethyl)py...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317225BDBM50317225((2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclopentyl)m...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317211BDBM50317211((2R)-N-(adamantan-2-yl)-1-propylpyrrolidine-2-carb...)
Affinity DataKi:  1nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317223BDBM50317223((2R)-N-(adamantan-2-yl)-1-(pyridin-2-yl)pyrrolidin...)
Affinity DataKi:  1nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317224BDBM50317224((2R)-N-(adamantan-2-yl)-1-(oxan-4-ylmethyl)pyrroli...)
Affinity DataKi:  1nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317213BDBM50317213((2R)-N-(adamantan-2-yl)-1-(cyclopentylmethyl)pyrro...)
Affinity DataKi:  1nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317217BDBM50317217((2R)-N-(adamantan-2-yl)-1-(2,2,2-trifluoroethyl)py...)
Affinity DataKi:  1nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317221BDBM50317221((2R)-N-(adamantan-2-yl)-1-[(3-cyanophenyl)methyl]p...)
Affinity DataKi:  1nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317218BDBM50317218((2R)-N-(adamantan-2-yl)-1-(3,3,3-trifluoropropyl)p...)
Affinity DataKi:  1nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317211BDBM50317211((2R)-N-(adamantan-2-yl)-1-propylpyrrolidine-2-carb...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317209BDBM50317209(PF-877423 | (2R)-N-(adamantan-2-yl)-1-ethylpyrroli...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317211BDBM50317211((2R)-N-(adamantan-2-yl)-1-propylpyrrolidine-2-carb...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317212BDBM50317212((2R)-N-(adamantan-2-yl)-1-(propan-2-yl)pyrrolidine...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317219BDBM50317219((2R)-N-(adamantan-2-yl)-1-[(4-chlorophenyl)methyl]...)
Affinity DataKi:  2nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317208BDBM50317208(N-(adamantan-2-yl)-2-[cyclohexyl(ethyl)amino]aceta...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317210BDBM50317210((2R)-N-(adamantan-2-yl)-1-methylpyrrolidine-2-carb...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317216BDBM50317216((2R)-N-(adamantan-2-yl)-1-(cyclohexylmethyl)pyrrol...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317208BDBM50317208(N-(adamantan-2-yl)-2-[cyclohexyl(ethyl)amino]aceta...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317212BDBM50317212((2R)-N-(adamantan-2-yl)-1-(propan-2-yl)pyrrolidine...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317216BDBM50317216((2R)-N-(adamantan-2-yl)-1-(cyclohexylmethyl)pyrrol...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317218BDBM50317218((2R)-N-(adamantan-2-yl)-1-(3,3,3-trifluoropropyl)p...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317222BDBM50317222((2R)-N-(adamantan-2-yl)-1-(2-hydroxyethyl)pyrrolid...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317209BDBM50317209(PF-877423 | (2R)-N-(adamantan-2-yl)-1-ethylpyrroli...)
Affinity DataIC50: 4.15nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317223BDBM50317223((2R)-N-(adamantan-2-yl)-1-(pyridin-2-yl)pyrrolidin...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317210BDBM50317210((2R)-N-(adamantan-2-yl)-1-methylpyrrolidine-2-carb...)
Affinity DataKi:  5.40nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317219BDBM50317219((2R)-N-(adamantan-2-yl)-1-[(4-chlorophenyl)methyl]...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317212BDBM50317212((2R)-N-(adamantan-2-yl)-1-(propan-2-yl)pyrrolidine...)
Affinity DataKi:  9.40nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317224BDBM50317224((2R)-N-(adamantan-2-yl)-1-(oxan-4-ylmethyl)pyrroli...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317207BDBM50317207(N-cyclohexyl-2-(7,8-dihydro-4H-isoxazolo[3,4-d]aze...)
Affinity DataKi:  15nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317224BDBM50317224((2R)-N-(adamantan-2-yl)-1-(oxan-4-ylmethyl)pyrroli...)
Affinity DataKi:  16nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317225BDBM50317225((2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclopentyl)m...)
Affinity DataKi:  17nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317222BDBM50317222((2R)-N-(adamantan-2-yl)-1-(2-hydroxyethyl)pyrrolid...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317210BDBM50317210((2R)-N-(adamantan-2-yl)-1-methylpyrrolidine-2-carb...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317217BDBM50317217((2R)-N-(adamantan-2-yl)-1-(2,2,2-trifluoroethyl)py...)
Affinity DataKi:  35.2nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317223BDBM50317223((2R)-N-(adamantan-2-yl)-1-(pyridin-2-yl)pyrrolidin...)
Affinity DataKi:  40nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317226BDBM50317226((2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclohexyl)me...)
Affinity DataKi:  48nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317221BDBM50317221((2R)-N-(adamantan-2-yl)-1-[(3-cyanophenyl)methyl]p...)
Affinity DataKi:  170nMAssay Description:Inhibition of mouse 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317206BDBM50317206((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...)
Affinity DataKi:  175nMAssay Description:Inhibition of human 11-beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317206BDBM50317206((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317207BDBM50317207(N-cyclohexyl-2-(7,8-dihydro-4H-isoxazolo[3,4-d]aze...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50317206BDBM50317206((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 11-beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed