Compile Data Set for Download or QSAR
maximum 50k data
Found 69 Enz. Inhib. hit(s) with all data for entry = 50031690
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306503(4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  20nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317333((S)-N-(3-fluoro-4-(2-(4-((N-(1-methoxypropan-2-yl)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317335(CHEMBL1095356 | N-(4-(2-(4-(dimethylcarbamoyl)phen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317336(CHEMBL1095357 | N-(4-(2-(4-((2-(dimethylamino)ethy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317338(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317339(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317337((S)-N-(4-(2-(4-(3-(dimethylamino)pyrrolidine-1-car...)
Affinity DataIC50:  40nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317338(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317340(CHEMBL1095361 | N-(4-(2-(1-acetyl-1,2,3,6-tetrahyd...)
Affinity DataIC50:  50nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317335(CHEMBL1095356 | N-(4-(2-(4-(dimethylcarbamoyl)phen...)
Affinity DataIC50:  50nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317334(CHEMBL1095036 | N-(3-fluoro-4-(2-(4-((2-(methylsul...)
Affinity DataIC50:  60nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317333((S)-N-(3-fluoro-4-(2-(4-((N-(1-methoxypropan-2-yl)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317332(CHEMBL1095034 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  60nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317330(CHEMBL1098157 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  60nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317339(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317331(1-tert-butyl-N-(3-fluoro-4-(2-(1-methyl-1H-imidazo...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317326(CHEMBL1086932 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317327(CHEMBL1086675 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317334(CHEMBL1095036 | N-(3-fluoro-4-(2-(4-((2-(methylsul...)
Affinity DataIC50:  80nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  80nMAssay Description:Inhibition of c-Met-mediated cell migration of human A549 cells by would healingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  80nMAssay Description:Inhibition of c-Met-mediated scattering in HGF-stimulated human DU145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317324(CHEMBL1087984 | N-(4-(6,7-dimethoxyquinolin-4-ylox...)
Affinity DataIC50:  80nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317328(CHEMBL1086676 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  80nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317340(CHEMBL1095361 | N-(4-(2-(1-acetyl-1,2,3,6-tetrahyd...)
Affinity DataIC50:  90nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317336(CHEMBL1095357 | N-(4-(2-(4-((2-(dimethylamino)ethy...)
Affinity DataIC50:  90nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317337((S)-N-(4-(2-(4-(3-(dimethylamino)pyrrolidine-1-car...)
Affinity DataIC50:  100nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306503(4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317326(CHEMBL1086932 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  150nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  150nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317332(CHEMBL1095034 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  150nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(CHEMBL462232 | N-(3-fluoro-4-(2-(1-methyl-1H-imida...)
Affinity DataIC50:  170nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317329(5-amino-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-y...)
Affinity DataIC50:  180nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317331(1-tert-butyl-N-(3-fluoro-4-(2-(1-methyl-1H-imidazo...)
Affinity DataIC50:  200nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317324(CHEMBL1087984 | N-(4-(6,7-dimethoxyquinolin-4-ylox...)
Affinity DataIC50:  200nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306507(4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  210nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317327(CHEMBL1086675 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  210nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  400nMAssay Description:Inhibition of c-Met-mediated cell migration of human A549 cells by would healingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306507(4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  410nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  500nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317328(CHEMBL1086676 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  590nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306507(4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  700nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317336(CHEMBL1095357 | N-(4-(2-(4-((2-(dimethylamino)ethy...)
Affinity DataIC50:  700nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317330(CHEMBL1098157 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  700nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317329(5-amino-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-y...)
Affinity DataIC50:  800nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317330(CHEMBL1098157 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317329(5-amino-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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