Compile Data Set for Download or QSAR
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Found 87 Enz. Inhib. hit(s) with all data for entry = 50032377
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328048(CHEMBL1257185)
Affinity DataIC50:  8nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328038(CHEMBL1258467 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328047(CHEMBL1257184 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328030(CHEMBL1258001 | N-((2S,3R)-4-(1-(3-tert-butyl-5-(m...)
Affinity DataIC50:  12nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328042(CHEMBL1258687 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328023(CHEMBL1257531 | N-((2S,3R)-4-(1-(3-tert-butyl-5-fl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302841(CHEMBL571860 | N-((2S,3R)-4-(1-(3-tert-butylphenyl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328046(CHEMBL1258918 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328037(CHEMBL1258466 | N-((2S,3R)-4-(1-(4-tert-butylthiop...)
Affinity DataIC50:  32nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328036(CHEMBL1258353 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328024(CHEMBL1257649 | N-((2S,3R)-4-(1-(3-bromo-5-tert-bu...)
Affinity DataIC50:  42nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328035(CHEMBL1258352 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  42nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328031(CHEMBL1258119 | N-((2S,3R)-4-(1-(3-acetyl-5-tert-b...)
Affinity DataIC50:  45nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328023(CHEMBL1257531 | N-((2S,3R)-4-(1-(3-tert-butyl-5-fl...)
Affinity DataIC50:  46nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328027(CHEMBL1257773 | N-((2S,3R)-4-(1-(3-tert-butyl-5-me...)
Affinity DataIC50:  47nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302841(CHEMBL571860 | N-((2S,3R)-4-(1-(3-tert-butylphenyl...)
Affinity DataIC50:  47nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328025(CHEMBL1257650 | N-((2S,3R)-4-(1-(3-tert-butyl-5-io...)
Affinity DataIC50:  55nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328026(CHEMBL1257772 | N-((2S,3R)-4-(1-(3-tert-butyl-5-me...)
Affinity DataIC50:  67nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328027(CHEMBL1257773 | N-((2S,3R)-4-(1-(3-tert-butyl-5-me...)
Affinity DataIC50:  77nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328028(CHEMBL1257891 | N-((2S,3R)-4-(1-(3-tert-butyl-5-hy...)
Affinity DataIC50:  90nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328030(CHEMBL1258001 | N-((2S,3R)-4-(1-(3-tert-butyl-5-(m...)
Affinity DataIC50:  93nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328037(CHEMBL1258466 | N-((2S,3R)-4-(1-(4-tert-butylthiop...)
Affinity DataIC50:  104nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328029(CHEMBL1257892 | N-((2S,3R)-4-(1-(3-amino-5-tert-bu...)
Affinity DataIC50:  105nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328022(CHEMBL1257530 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  125nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328038(CHEMBL1258467 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  131nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328042(CHEMBL1258687 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  139nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328050(CHEMBL1257303 | N-((2S,3R)-4-(1-(3-tert-butylpheny...)
Affinity DataIC50:  140nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328045(CHEMBL1258917 | N-((2S,3R)-4-(1-(1-tert-butyl-1H-p...)
Affinity DataIC50:  140nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328047(CHEMBL1257184 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  154nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328031(CHEMBL1258119 | N-((2S,3R)-4-(1-(3-acetyl-5-tert-b...)
Affinity DataIC50:  160nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328028(CHEMBL1257891 | N-((2S,3R)-4-(1-(3-tert-butyl-5-hy...)
Affinity DataIC50:  170nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328024(CHEMBL1257649 | N-((2S,3R)-4-(1-(3-bromo-5-tert-bu...)
Affinity DataIC50:  174nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328026(CHEMBL1257772 | N-((2S,3R)-4-(1-(3-tert-butyl-5-me...)
Affinity DataIC50:  180nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328063(CHEMBL1258121 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328046(CHEMBL1258918 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328025(CHEMBL1257650 | N-((2S,3R)-4-(1-(3-tert-butyl-5-io...)
Affinity DataIC50:  223nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328040(CHEMBL1258576 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  228nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328049(CHEMBL1257302 | N-((2S,3R)-4-(1-(6-tert-butylpyrim...)
Affinity DataIC50:  245nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328041(CHEMBL1258686 | N-((2S,3R)-4-(1-(3-tert-butylisoxa...)
Affinity DataIC50:  263nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328039(CHEMBL1258575 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  276nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328050(CHEMBL1257303 | N-((2S,3R)-4-(1-(3-tert-butylpheny...)
Affinity DataIC50:  290nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328043(CHEMBL1258802 | N-((2S,3R)-4-(1-(5-tert-butyloxazo...)
Affinity DataIC50:  310nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328029(CHEMBL1257892 | N-((2S,3R)-4-(1-(3-amino-5-tert-bu...)
Affinity DataIC50:  318nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328035(CHEMBL1258352 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  320nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328051(CHEMBL1257417 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  341nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328061(CHEMBL1258002 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  346nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328036(CHEMBL1258353 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  352nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328051(CHEMBL1257417 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  379nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328048(CHEMBL1257185)
Affinity DataIC50:  392nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328056(CHEMBL1230648 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  395nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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