Compile Data Set for Download or QSAR
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Found 13 Enz. Inhib. hit(s) with all data for entry = 50033273
TargetAcetylcholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  5nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataIC50:  6nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  12nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  49nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  54nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  100nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  200nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  350nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank