Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50033132
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50146453(3-(4-methoxyphenyl)acrylic acid | para-methoxycinn...)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340097(5-(4-(2-hydroxyethoxy)benzylidene)-2-thioxothiazol...)
Affinity DataIC50: 5.60E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340096(5-(3, 4-bis(2-hydroxyethoxy)benzylidene)-2-thioxot...)
Affinity DataIC50: 5.69E+6nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50092273((Z)-5-(2'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50: 9.55E+6nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50247599((Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50: 1.01E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50219502(4-hydroxyphenyl beta-D-glucopyranoside | hydroquin...)
Affinity DataIC50: 1.04E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340094(1-(4-ethyl-6-methyl-2-thioxo-1,2,3,4-tetrahydropyr...)
Affinity DataIC50: 1.07E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340098(5-(4-hydroxy-3-methoxybenzylidene)-2-thioxothiazol...)
Affinity DataIC50: 1.11E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340095(1-(4-(4-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataIC50: 1.23E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340091(1-(4-(2-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataIC50: 1.63E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340092(1-(4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-thioxo...)
Affinity DataIC50: 2.01E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340093(1-(4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataIC50: 2.51E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed